Submissions from 2021
An Empirical Pipeline for Personalized Diagnosis of Lafora Disease Mutations, M. Kathryn Brewer, Maria Machio-Castello, Rosa Viana, Jeremiah L. Wayne, Andrea Kuchtová, Zoe R. Simmons, Sarah Sternbach, Sheng Li, Maria Adelaida García-Gimeno, Jose M. Serratosa, Pascual Sanz, Craig W. Vander Kooi, and Matthew S. Gentry
Submissions from 2020
Polyglucosan Body Structure in Lafora Disease, M. Kathryn Brewer, Jean-Luc Putaux, Alberto Rondon, Annette M. Uittenbogaard, Mitchell A. Sullivan, and Matthew S. Gentry
Calcineurin, Trevor P. Creamer
NEK1 Phosphorylation of YAP Promotes Its Stabilization and Transcriptional Output, Md Imtiaz Khalil, Ishita Ghosh, Vibha Singh, Jing Chen, Haining Zhu, and Arrigo De Benedetti
Submissions from 2018
Insulin-Degrading Enzyme Is Not Secreted From Cultured Cells, Eun Suk Song, David W. Rodgers, and Louis Hersh
Submissions from 2017
Structure and Specificity of a Permissive Bacterial C-Prenyltransferase, Sherif I. Elshahawi, Hongnan Cao, Khaled A. Shaaban, Larissa V. Ponomareva, Thangaiah Subramanian, Mark L. Farman, H. Peter Spielmann, George N. Phillips Jr., Jon S. Thorson, and Shanteri Singh
Down Syndrome: Age-Dependence of PiB Binding in Postmortem Frontal Cortex Across the Lifespan, Harry LeVine III, H. Peter Spielmann, Sergey V. Matveev, Francesca Macchiavello Cauvi, M. Paul Murphy, Tina L. Beckett, Katie McCarty, Ira T. Lott, Eric Doran, Frederick A. Schmitt, and Elizabeth Head
Quaternary Interactions and Supercoiling Modulate the Cooperative DNA Binding of AGT, Manana Melikishvili and Michael G. Fried
Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase, Warintra Pitsawong, Chad A. Haynes, Ronald L. Koder, David W. Rodgers, and Anne-Frances Miller
1H, 15N, and 13C Chemical Shift Assignments of the Regulatory Domain of Human Calcineurin, Dinesh K. Yadav, Sri Ramya Tata, John Hunt, Erik C. Cook, Trevor P. Creamer, and Nicholas C. Fitzkee
Submissions from 2016
Targeting an Essential GTPase Obg for the Development of Broad-Spectrum Antibiotics, Josephine A. Bonventre, Ryszard A. Zielke, Konstantin V. Korotkov, and Aleksandra E. Sikora
P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer, Hira Lal Goel, Bryan Pursell, Leonard D. Shultz, Dale L. Greiner, Rolf A Brekken, Craig W. Vander Kooi, and Arthur M. Mercurio
Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes, Vincent J. C. van Winden, Roy Ummels, Sander R. Piersma, Connie R. Jiménez, Konstantin V. Korotkov, Wilbert Bitter, and Edith N. G. Houben
Structures of EccB1 and EccD1 from the Core Complex of the Mycobacterial ESX-1 Type VII Secretion System, Jonathan Mark Wagner, Sum Chan, Timothy J. Evans, Sara Kahng, Jennifer Kim, Mark A. Arbing, David Eisenberg, and Konstantin V. Korotkov
Submissions from 2015
Mechanistic Insights into Glucan Phosphatase Activity against Polyglucan Substrates, David A. Meekins, Madushi Raththagala, Kyle D. Auger, Benjamin D. Turner, Diana Santelia, Oliver Kötting, Matthew S. Gentry, and Craig W. Vander Kooi
Structural Mechanism of Laforin Function in Glycogen Dephosphorylation and Lafora Disease, Madushi Raththagala, M. Kathryn Brewer, Matthew W. Parker, Amanda R. Sherwood, Brian K. Wong, Simon Hsu, Travis M. Bridges, Bradley C. Paasch, Lance M. Hellman, Satrio Husodo, David A. Meekins, Adam O. Taylor, Benjamin D. Turner, Kyle D. Auger, Vikas V. Dukhande, Srinivas Chakravarthy, Pascual Sanz, Virgil L. Woods Jr., Sheng Li, Craig Vander Kooi, and Matthew S. Gentry
An Extended Polyanion Activation Surface in Insulin Degrading Enzyme, Eun Suk Song, Mehmet Ozbil, Tingting Zhang, Michael Sheetz, David Lee, Danny Tran, Sheng Li, Rajeev Prabhakar, Louis B. Hersh, and David W. Rodgers
Submissions from 2014
Expression, Purification and Characterization of Soluble Red Rooster Laforin as a Fusion Protein in Escherichia Coli, M. Kathryn Brewer, Satrio Husodo, Vikas V. Dukhande, Mary Beth Johnson, and Matthew S. Gentry
Submissions from 2013
Thermodynamics of Binding by Calmodulin Correlates with Target Peptide α-Helical Propensity, Tori B. Dunlap, Jessime M. Kirk, Emily A. Pena, Meghan S. Yoder, and Trevor P. Creamer
Assembly of the type II secretion system such as found in Vibrio cholerae depends on the novel Pilotin AspS, Rhys A. Dunstan, Eva Heinz, Lakshmi C. Wijeyewickrema, Robert N. Pike, Anthony W. Purcell, Timothy J. Evans, Judyta Praszkier, Roy M. Robins-Browne, Richard A. Strugnell, Konstantin V. Korotkov, and Trevor Lithgow
Functional Integration of the Conserved Domains of Shoc2 Scaffold, Myoungkun Jeoung, Lina Abdelmoti, Eun Ryoung Jang, Craig W. Vander Kooi, and Emilia Galperin
Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus, Praveen R. Juvvadi, Christopher Gehrke, Jarrod R. Fortwendel, Frédéric Lamoth, Erik J. Soderblom, Erik C. Cook, Michael A. Hast, Yohannes G. Asfaw, M. Arthur Moseley, Trevor P. Creamer, and William J. Steinbach
Dimerization of the glucan phosphatase laforin requires the participation of cysteine 329, Pablo Sánchez-Martín, Madushi Raththagala, Travis M. Bridges, Satrio Husodo, Matthew S. Gentry, Pascual Sanz, and Carlos Romá-Mateo
Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure, Manli Shen, Stanislav Bellaousov, Michael Hiller, Pierre de La Grange, Trevor O. Creamer, Orit Malina, Ruth Sperling, David H. Mathews, Peter Stoilov, and Stefan Stamm
Submissions from 2012
Lesion-Specific DNA-Binding and Repair Activities of Human O⁶-Alkylguanine DNA Alkyltransferase, Manana Melikishvili and Michael G. Fried
