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Submissions from 2021

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Mechanisms of Smoothened Regulation in Hedgehog Signaling, Jie Zhang, Zulong Liu, and Jianhang Jia

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Co-Targeting Plk1 and DNMT3a in Advanced Prostate Cancer, Zhuangzhuang Zhang, Lijun Cheng, Qiongsi Zhang, Yifan Kong, Daheng He, Kunyu Li, Matthew Rea, Jianlin Wang, Ruixin Wang, Jinghui Liu, Zhiguo Li, Chongli Yuan, Enze Liu, Yvonne N. Fondufe-Mittendorf, Lang Li, Tao Han, Chi Wang, and Xiaoqi Liu

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CD151 Drives Cancer Progression Depending on Integrin α3β1 through EGFR Signaling in Non-Small Cell Lung Cancer, Jianjie Zhu, Tingting Cai, Jieqi Zhou, Wenwen Du, Yuanyuan Zeng, Ting Liu, Yulong Fu, Yue Li, Qian Qian, Xiuwei H. Yang, Qinglin Li, Jian-an Huang, and Zeyi Liu

Submissions from 2020

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Spatial Profiling of Gangliosides in Mouse Brain by Mass Spectrometry Imaging, Douglas A. Andres, Lyndsay E. A. Young, Matthew S. Gentry, and Ramon C. Sun

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Viral Membrane Fusion and the Transmembrane Domain, Chelsea T. Barrett and Rebecca Ellis Dutch

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Polyglucosan Body Structure in Lafora Disease, M. Kathryn Brewer, Jean-Luc Putaux, Alberto Rondon, Annette M. Uittenbogaard, Mitchell A. Sullivan, and Matthew S. Gentry

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Modulation of Epileptogenesis: A Paradigm for the Integration of Enzyme-Based Microelectrode Arrays and Optogenetics, Corwin R. Butler, Jeffery A. Boychuk, Francois Pomerleau, Ramona Alcala, Peter Huettl, Yi Ai, Johan Jakobsson, Sidney W. Whiteheart, Greg A. Gerhardt, Bret N. Smith, and John T. Slevin

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Calcineurin, Trevor P. Creamer

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GOcats: A Tool for Categorizing Gene Ontology into Subgraphs of User-Defined Concepts, Eugene Waverly Hinderer III and Hunter N. B. Moseley

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Atom Identifiers Generated by a Neighborhood-Specific Graph Coloring Method Enable Compound Harmonization across Metabolic Databases, Huan Jin, Joshua M. Mitchell, and Hunter N. B. Moseley

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CCL2 Overexpression in the Brain Promotes Glial Activation and Accelerates Tau Pathology in a Mouse Model of Tauopathy, Aurelie Joly-Amado, Jordan Hunter, Zainuddin Quadri, Frank Zamudio, Patricia V. Rocha-Rangel, Deanna Chan, Anisha Kesarwani, Kevin Nash, Daniel C. Lee, Dave Morgan, Marcia N. Gordon, and Maj-Linda B. Selenica

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NEK1 Phosphorylation of YAP Promotes Its Stabilization and Transcriptional Output, Md Imtiaz Khalil, Ishita Ghosh, Vibha Singh, Jing Chen, Haining Zhu, and Arrigo De Benedetti

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Frontotemporal Dementia Nonsense Mutation of Progranulin Rescued by Aminoglycosides, Lisha Kuang, Kei Hashimoto, Eric J. Huang, Matthew S. Gentry, and Haining Zhu

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Hypusination of Eif5a Regulates Cytoplasmic TDP-43 Aggregation and Accumulation in a Stress-Induced Cellular Model, Shayna Smeltzer, Zainuddin Quadri, Abraian Miller, Frank Zamudio, Jordan Hunter, Nicholas J.F. Stewart, Sheba Saji, Daniel C. Lee, Dale Chaput, and Maj-Linda B. Selenica

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Characterization and Enzyme Engineering of a Hyperthermophilic Laccase toward Improving Its Activity in Ionic Liquid, Joseph Craig Stevens, David W. Rodgers, Claire Dumon, and Jian Shi

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Protein Tyrosine Phosphatase 4A3 (PTP4A3/PRL-3) Drives Migration and Progression of T-Cell Acute Lymphoblastic Leukemia in Vitro and in Vivo, Min Wei, Meghan G. Haney, Dylan R. Rivas, and Jessica S. Blackburn

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Hsp47 Promotes Cancer Metastasis by Enhancing Collagen-Dependent Cancer Cell-Platelet Interaction, Gaofeng Xiong, Jie Chen, Guoying Zhang, Shike Wang, Kunito Kawasaki, Jieqing Zhu, Yan Zhang, Kazuhiro Nagata, Zhenyu Li, Binhua P. Zhou, and Ren Xu

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Upregulation of CPT1A Is Essential for the Tumor-Promoting Effect of Adipocytes in Colon Cancer, Xiaopeng Xiong, Yang-An Wen, Rachelle Fairchild, Yekaterina Y. Zaytseva, Heidi L. Weiss, B. Mark Evers, and Tianyan Gao

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A Chemical Interpretation of Protein Electron Density Maps in the Worldwide Protein Data Bank, Sen Yao and Hunter N. B. Moseley

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TDP-43 Mediated Blood-Brain Barrier Permeability and Leukocyte Infiltration Promote Neurodegeneration in a Low-Grade Systemic Inflammation Mouse Model, Frank Zamudio, Anjanet R. Loon, Shayna Smeltzer, Khawla Benyamine, Nanda K. Navalpur Shanmugam, Nicholas J. F. Stewart, Daniel C. Lee, Kevin Nash, and Maj-Linda B. Selenica

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Epigenetic Regulation of Wnt Signaling by Carboxamide-Substituted Benzhydryl Amines that Function as Histone Demethylase Inhibitors, Wen Zhang, Vitaliy M. Sviripa, Yanqi Xie, Tianxin Yu, Meghan G. Haney, Jessica S. Blackburn, Charles A. Adeniran, Chang-Guo Zhan, David S. Watt, and Chunming Liu

Submissions from 2019

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Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion, M. Kathryn Brewer, Annette M. Uittenbogaard, Grant L. Austin, Dyann M. Segvich, Anna DePaoli-Roach, Peter J. Roach, John J. McCarthy, Zoe R. Simmons, Jason A. Brandon, Zhengqiu Zhou, Jill Zeller, Lyndsay E. A. Young, Ramon C. Sun, James R. Pauly, Nadine M. Aziz, Bradley L. Hodges, Tracy R. McKnight, Dustin D. Armstrong, and Matthew S. Gentry

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ITCH Nuclear Translocation and H1.2 Polyubiquitination Negatively Regulate the DNA Damage Response, Lufen Chang, Lei Shen, Hu Zhou, Jing Gao, Hangyi Pan, Li Zheng, Brian Armstrong, Yang Peng, Guang Peng, Binhua P. Zhou, Steven T. Rosen, and Binghui Shen

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BaMORC: A Software Package for Accurate and Robust 13C Reference Correction of Protein NMR Spectra, Xi Chen, Andrey Smelter, and Hunter N. B. Moseley

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Immunization of Alpacas (Lama pacos) with Protein Antigens and Production of Antigen-Specific Single Domain Antibodies, K. Martin Chow, Sidney W. Whiteheart, Jeffrey R. Smiley, Savita Sharma, Kathy Boaz, Meggie J. Coleman, Alvina Maynard, Louis B. Hersh, and Craig W. Vander Kooi