Follow


Submissions from 2016

PDF

P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer, Hira Lal Goel, Bryan Pursell, Leonard D. Shultz, Dale L. Greiner, Rolf A Brekken, Craig W. Vander Kooi, and Arthur M. Mercurio

PDF

Structures of EccB1 and EccD1 from the Core Complex of the Mycobacterial ESX-1 Type VII Secretion System, Jonathan Mark Wagner, Sum Chan, Timothy J. Evans, Sara Kahng, Jennifer Kim, Mark A. Arbing, David Eisenberg, and Konstantin V. Korotkov

Submissions from 2015

PDF

Mechanistic Insights into Glucan Phosphatase Activity against Polyglucan Substrates, David A. Meekins, Madushi Raththagala, Kyle D. Auger, Benjamin D. Turner, Diana Santelia, Oliver Kötting, Matthew S. Gentry, and Craig W. Vander Kooi

PDF

Structural Mechanism of Laforin Function in Glycogen Dephosphorylation and Lafora Disease, Madushi Raththagala, M. Kathryn Brewer, Matthew W. Parker, Amanda R. Sherwood, Brian K. Wong, Simon Hsu, Travis M. Bridges, Bradley C. Paasch, Lance M. Hellman, Satrio Husodo, David A. Meekins, Adam O. Taylor, Benjamin D. Turner, Kyle D. Auger, Vikas V. Dukhande, Srinivas Chakravarthy, Pascual Sanz, Virgil L. Woods Jr., Sheng Li, Craig Vander Kooi, and Matthew S. Gentry

PDF

An Extended Polyanion Activation Surface in Insulin Degrading Enzyme, Eun Suk Song, Mehmet Ozbil, Tingting Zhang, Michael Sheetz, David Lee, Danny Tran, Sheng Li, Rajeev Prabhakar, Louis B. Hersh, and David W. Rodgers

Submissions from 2014

PDF

Expression, Purification and Characterization of Soluble Red Rooster Laforin as a Fusion Protein in Escherichia Coli, M. Kathryn Brewer, Satrio Husodo, Vikas V. Dukhande, Mary Beth Johnson, and Matthew S. Gentry

Submissions from 2013

PDF

Thermodynamics of Binding by Calmodulin Correlates with Target Peptide α-Helical Propensity, Tori B. Dunlap, Jessime M. Kirk, Emily A. Pena, Meghan S. Yoder, and Trevor P. Creamer

PDF

Assembly of the type II secretion system such as found in Vibrio cholerae depends on the novel Pilotin AspS, Rhys A. Dunstan, Eva Heinz, Lakshmi C. Wijeyewickrema, Robert N. Pike, Anthony W. Purcell, Timothy J. Evans, Judyta Praszkier, Roy M. Robins-Browne, Richard A. Strugnell, Konstantin V. Korotkov, and Trevor Lithgow

PDF

Functional Integration of the Conserved Domains of Shoc2 Scaffold, Myoungkun Jeoung, Lina Abdelmoti, Eun Ryoung Jang, Craig W. Vander Kooi, and Emilia Galperin

PDF

Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus, Praveen R. Juvvadi, Christopher Gehrke, Jarrod R. Fortwendel, Frédéric Lamoth, Erik J. Soderblom, Erik C. Cook, Michael A. Hast, Yohannes G. Asfaw, M. Arthur Moseley, Trevor P. Creamer, and William J. Steinbach

PDF

Dimerization of the glucan phosphatase laforin requires the participation of cysteine 329, Pablo Sánchez-Martín, Madushi Raththagala, Travis M. Bridges, Satrio Husodo, Matthew S. Gentry, Pascual Sanz, and Carlos Romá-Mateo

PDF

Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure, Manli Shen, Stanislav Bellaousov, Michael Hiller, Pierre de La Grange, Trevor O. Creamer, Orit Malina, Ruth Sperling, David H. Mathews, Peter Stoilov, and Stefan Stamm

Submissions from 2012

PDF

Lesion-Specific DNA-Binding and Repair Activities of Human O⁶-Alkylguanine DNA Alkyltransferase, Manana Melikishvili and Michael G. Fried

PDF

FUS-NLS/Transportin 1 complex structure provides insights into the nuclear targeting mechanism of FUS and the implications in ALS, Chunyan Niu, Jiayu Zhang, Feng Gao, Liuqing Yang, Minze Jia, Haining Zhu, and Weimin Gong

PDF

Structural Basis for Activation of Calcineurin by Calmodulin, Julie Rumi-Masante, Farai I. Rusinga, Terrence E. Lester, Tori B. Dunlap, Todd D. Williams, A. Keith Dunker, David D. Weis, and Trevor P. Creamer

PDF

Role of Sequence and Structure of the Hendra Fusion Protein Fusion Peptide in Membrane Fusion, Everett Clinton Smith, Sonia M. Gregory, Lukas K. Tamm, Trevor P. Creamer, and Rebecca Ellis Dutch

PDF

Cysteine 904 is required for maximal insulin degrading enzyme activity and polyanion activation, Eun Suk Song, Manana Melikishvili, Michael G. Fried, Maria A. Juliano, Luiz Juliano, David W. Rodgers, and Louis B. Hersh

PDF

Cooperative Cluster Formation, DNA Bending and Base-Flipping by O6-Alkylguanine-DNA Alkyltransferase, Ingrid Tessmer, Manana Melikishvili, and Michael G. Fried

Submissions from 2011

PDF

Laforin, a dual specificity phosphatase involved in Lafora disease, is present mainly as monomeric form with full phosphatase activity, Vikas V. Dukhande, Devin M. Rogers, Carlos Romá-Mateo, Jordi Donderis, Alberto Marina, Adam O. Taylor, Pascual Sanz, and Matthew S. Gentry

PDF

Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19, Liping Ren, Janel R. McLean, Tony R. Hazbun, Stanley Fields, Craig Vander Kooi, Melanie D. Ohi, and Kathleen L. Gould

PDF

Lafora disease E3-ubiquitin ligase malin is related to TRIM32 at both the phylogenetic and functional level, Carlos Romá-Mateo, Daniel Moreno, Santiago Vernia, Teresa Rubio, Travis M. Bridges, Matthew S. Gentry, and Pascual Sanz

Submissions from 2009

PDF

DNA-binding by Haemophilus influenzae and Escherichia coli YbaB, members of a widely-distributed bacterial protein family, Anne E. Cooley, Sean P. Riley, Keith Kral, M. Clarke Miller, Edward DeMoll, Michael G. Fried, and Brian Stevenson

Submissions from 2008

PDF

Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis, Young-In Chi, Monika Martick, Monica Lares, Rosalind Kim, William G. Scott, and Sung-Hou Kim

Submissions from 2002

Link

Polyproline II Helical Structure in Protein Unfolded States: Lysine Peptides Revisited, Adam L. Rucker and Trevor P. Creamer

Submissions from 1999

Link

A Survey of Left-Handed Polyproline II Helices, B. J. Stapley and Trevor P. Creamer