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Abstract

Sepsis remains a significant medical problem. TNFα is a central cytokine in sepsis pathophysiology. We conducted a phase IIa trial in patients with severe sepsis to assess the safety and tolerability of an intravenously infused ovine-derived polyclonal anti-TNFα Fab fragment (AZD9773).

Document Type

Presentation

Publication Date

3-11-2011

Notes/Citation Information

Published in Critical Care, v. 15 (Suppl. 1): P263.

© 2011 Morris et al.

From the 31st International Symposium on Intensive Care and Emergency Medicine (Brussels, Belgium: 22-25 March 2011).

Digital Object Identifier (DOI)

http://dx.doi.org/10.1186/cc9683

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