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Submissions from 2014

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Con: Are We Ready to Translate Alzheimer's Disease-Modifying Therapies to People with Down Syndrome?, Elizabeth Head and Frederick A. Schmitt

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Alzheimer's Therapeutics Targeting Amyloid Beta 1-42 Oligomers I: Abeta 42 Oligomer Binding to Specific Neuronal Receptors is Displaced by Drug Candidates That Improve Cognitive Deficits, Nicholas J. Izzo, Agnes Staniszewski, Lillian To, Mauro Fa, Andrew F. Teich, Faisal Saeed, Harrison Wostein, Thomas Walko III, Anisha Vaswani, Meghan Wardius, Zanobia Syed, Jessica Ravenscroft, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Patricia Finn, Gary Look, Gilbert Rishton, Hank Safferstein, Miles Miller, Conrad Johanson, Edward Stopa, Manfred Windisch, Birgit Hutter-Paier, Mehrdad Shamloo, Ottavio Arancio, Harry LeVine III, and Susan M. Catalano

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Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers II: Sigma-2/PGRMC1 Receptors Mediate Abeta 42 Oligomer Binding and Synaptotoxicity, Nicholas J. Izzo, Jinbin Xu, Chenbo Zeng, Molly J. Kirk, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Gary Look, Gilbert Rishton, Hank Safferstein, Carlos Cruchaga, Alison Goate, Michael A. Cahill, Ottavio Arancio, Robert H. Mach, Rolf Craven, Elizabeth Head, Harry LeVine III, Tara L. Spires-Jones, and Susan M. Catalano

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Self-Reported Memory Complaints: Implications from a Longitudinal Cohort with Autopsies, Richard J. Kryscio, Erin L. Abner, Gregory E. Cooper, David W. Fardo, Greg A. Jicha, Peter T. Nelson, Charles D. Smith, Linda J. Van Eldik, Lijie Wan, and Frederick A. Schmitt

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Vitamin D Prevents Cognitive Decline and Enhances Hippocampal Synaptic Function in Aging Rats, Caitlin S. Latimer, Lawrence D. Brewer, James L. Searcy, Kuey-Chu Chen, Jelena Popovic, Susan D. Kraner, Olivier Thibault, Eric M. Blalock, Philip W. Landfield, and Nada M. Porter

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Sugihara Causality Analysis of Scalp EEG for Detection of Early Alzheimer's Disease, Joseph C. McBride, Xiaopeng Zhao, Nancy B. Munro, Greg A. Jicha, Frederick A. Schmitt, Richard J. Kryscio, Charles D. Smith, and Yang Jiang

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ABCC9 Gene Polymorphism Is Associated with Hippocampal Sclerosis of Aging Pathology, Peter T. Nelson, Steven Estus, Erin L. Abner, Ishita Parikh, Manasi Malik, Janna H. Neltner, Eseosa Ighodaro, Wang-Xia Wang, Bernard R. Wilfred, Li-San Wang, Walter A. Kukull, Kannabiran Nandakumar, Mark L. Farman, Wayne W. Poon, Maria M. Corrada, Claudia H. Kawas, David H. Cribbs, David A. Bennett, Julie A. Schneider, Eric B. Larson, Paul K. Crane, Otto Valladares, Frederick A. Schmitt, Richard J. Kryscio, Gregory A. Jicha, Charles D. Smith, Stephen W. Scheff, Joshua A. Sonnen, Jonathan L. Haines, Margaret A. Pericak-Vance, Richard Mayeux, Lindsay A. Farrer, Linda J. Van Eldik, Craig Horbinski, Robert C. Green, Marla Gearing, Leonard W. Poon, Patricia L. Kramer, Randall L. Woltjer, Thomas J. Montine, Amanda B. Partch, Alexander J. Rajic, Katierose Richmire, Sarah E. Monsell, Gerard D. Schellenberg, and David W. Fardo

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Obesity and Diabetes Cause Cognitive Dysfunction in the Absence of Accelerated β-Amyloid Deposition in a Novel Murine Model of Mixed or Vascular Dementia, Dana M. Niedowicz, Valerie L. Reeves, Thomas L. Platt, Katharina Kohler, Tina L. Beckett, David K. Powell, Tiffany L. Lee, Travis R. Sexton, Eun Suk Song, Lawrence D. Brewer, Caitlin S. Latimer, Susan D. Kraner, Kara L. Larson, Sabire Özcan, Christopher M. Norris, Louis B. Hersh, Nada M. Porter, Donna M. Wilcock, and Michael Paul Murphy

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Genetics of PICALM Expression and Alzheimer's Disease, Ishita Parikh, David W. Fardo, and Steven Estus

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An Intronic PICALM Polymorphism, rs588076, Is Associated with Allelic Expression of a PICALM Isoform, Ishita Parikh, Christopher Medway, Steven Younkin, David Fardo, and Steven Estus

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Frontal White Matter Integrity in Adults with Down Syndrome with and without Dementia, David K. Powell, Allison Caban-Holt, Greg A. Jicha, William C. Robertson, Roberta Davis, Brian T. Gold, Frederick A. Schmitt, and Elizabeth Head

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Diffuse Brain Injury Induces Acute Post-Traumatic Sleep, Rachel K. Rowe, Martin Striz, Adam D. Bachstetter, Linda J. Van Eldik, Kevin D. Donohue, Bruce F. O'Hara, and Jonathan Lifshitz

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β-Amyloid Deposition is Shifted to the Vasculature and Memory Impairment is Exacerbated When Hyperhomocysteinemia is Induced in APP/PS1 Transgenic Mice, Tiffany L. Sudduth, Erica M. Weekman, Holly M. Brothers, Kaitlyn Braun, and Donna M. Wilcock

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Nutrition and Prevention of Alzheimer's Dementia, Arun Swaminathan and Gregory A. Jicha

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Soluble apoE/Aβ Complex: Mechanism and Therapeutic target for APOE4-induced AD Risk, Leon M. Tai, Shipra Mehra, Varsha Shete, Steven Estus, G. William Rebeck, Guojun Bu, and Mary Jo LaDu

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Expression of miR-15/107 Family MicroRNAs in Human Tissues and Cultured Rat Brain Cells, Wang-Xia Wang, Robert J. Danaher, Craig S. Miller, Joseph R. Berger, Vega G. Nubia, Bernard R. Wilfred, Janna H. Neltner, Christopher M. Norris, and Peter T. Nelson

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Transition from an M1 to a Mixed Neuroinflammatory Phenotype Increases Amyloid Deposition in APP/PS1 Transgenic Mice, Erica M. Weekman, Tiffany L. Sudduth, Erin L. Abner, Gabriel J. Popa, Michael D. Mendenhall, Holly M. Brothers, Kaitlyn Braun, Abigail Greenstein, and Donna M. Wilcock

Submissions from 2013

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Dose- and Time-Dependent Neuroprotective Effects of Pycnogenol® following Traumatic Brain Injury, Mubeen A. Ansari, Kelly N. Roberts, and Stephen W. Scheff

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The p38α MAPK Regulates Microglial Responsiveness to Diffuse Traumatic Brain Injury, Adam D. Bachstetter, Rachel K. Rowe, Machi Kaneko, Danielle Goulding, Jonathan Lifshitz, and Linda J Van Eldik

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Clinically relevant intronic splicing enhancer mutation in myelin proteolipid protein leads to progressive microglia and astrocyte activation in white and gray matter regions of the brain, Adam D. Bachstetter, Scott J. Webster, Linda J. Van Eldik, and Franca Cambi

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Dopaminergic Modulation of Memory and Affective Processing in Parkinson Depression, Lee X. Blonder, John T. Slevin, Richard J. Kryscio, Catherine A. Martin, Anders H. Andersen, Charles D Smith, and Frederick A. Schmitt

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Amyloid β-Peptide (1–42)-Induced Oxidative Stress in Alzheimer Disease: Importance in Disease Pathogenesis and Progression, D. Allan Butterfield, Aaron M. Swomley, and Rukhsana Sultana

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Intracranial injection of AAV expressing NEP but not IDE reduces amyloid pathology in APP+PS1 transgenic mice, Nikisha Carty, Kevin R. Nash, Milene Brownlow, Dana Cruite, Donna M. Wilcock, Maj-Linda B. Selenica, Daniel C. Lee, Marcia N. Gordon, and Dave Morgan

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Circulating MicroRNAs in Alzheimer's Disease: The Search for Novel Biomarkers, Véronique Dorval, Peter T. Nelson, and Sébastien S. Hébert

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Comparing Clinical Profiles in Alzheimer's Disease and Parkinson's Disease Dementia, Martin R. Farlow, Frederick A. Schmitt, Dag Aarsland, George T. Grossberg, Monique Somogyi, and Xiangyi Meng