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Abstract
Objective: Musculoskeletal injuries pose a health threat to U.S. Service members. In particular, the physical demands of walking and running with load carriage contribute to a high incidence of musculoskeletal injuries of the lower back. Active ankle exoskeleton devices are promising technologies that may help mitigate the impact of load carriage on the incidence of these injuries. However, the safe extended use of these devices requires an understanding of their beneficial or detrimental effects on the lumbar spine. In this pilot study, we investigated the impact of walking with an ankle exoskeleton device on lumbar biomechanical responses.
Methods: We collected motion-capture data and computed tomography images for five young, healthy men walking with a 22.7 kg (50-lb) load for 5 km at a speed of 1.3 m/s, with and without an active ankle exoskeleton (ExoBoot EB60). We developed individualized musculoskeletal and finite-element models to characterize the effects of walking distance and ExoBoot use on the trunk flexion angle, joint reaction force at the L4-L5 joint, and stress on the L4-L5 intervertebral disc annulus.
Results: While not statistically significant, we found that the peak trunk flexion angle and the peak annulus stress increased by 16% and 12%, respectively, after walking 5 km with the ExoBoot, and by 34% and 25%, respectively, without it. Similarly, the peak L4-L5 joint reaction force minimally increased by 4% with the ExoBoot, while it increased by 22% without the device.
Conclusion: ExoBoot use likely attenuates the effect of fatigue on the lumbar spine induced by walking with load carriage.
Document Type
Article
Publication Date
2025
Digital Object Identifier (DOI)
https://doi.org/10.3389/fbioe.2025.1654585
Funding Information
The author(s) declare that financial support was received for the research and/or publication of this article. This work was sponsored by the Military Operational Medicine Program Area Directorate of the U.S. Army Medical Research and Development Command (USAMRDC), Fort Detrick, MD. The Henry M. Jackson Foundation was supported by the USAMRDC under Contract Nos. W81XWH20C0031 and HT942524C0031. In addition, MAS was partly supported by the National Institutes of Health (K01-AG073698).
Repository Citation
Rubio, Jose E.; Tong, Junfei; Sundaramurthy, Aravind; Pant, Anup; Nagaraja, Sridevi; Owen, Meredith K.; Samaan, Michael A.; Noehren, Brian W.; and Reifman, Jaques, "Effect of walking with an active ankle exoskeleton on the biomechanical responses of the lumbar spine" (2025). Physical Therapy Faculty Publications. 143.
https://uknowledge.uky.edu/rehabsci_facpub/143

Notes/Citation Information
© 2025 Rubio, Tong, Sundaramurthy, Pant, Nagaraja, Owen, Samaan, Noehren and Reifman. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.