US Patent Number
Described herein are methods for treating cancer in a subject in need thereof by administering chloroquine, or a salt or prodrug thereof, optionally with another agent that promotes Par-4 production to induce prostate apoptosis response-4 (Par-4) production by host cells, particularly non-cancerous host cells, to promote apoptosis in cancer cells, including androgen insensitive prostate cancer cells.
The University of Kentucky Research Foundation, Lexington, KY (US)
Rangnekar, Vivek M., "Chloroquine Induction Par-4 and Treatment of Cancer" (2019). Radiation Medicine Faculty Patents. 2.