US Patent Number
10,512,641
Publication Date
12-24-2019
Abstract
Described herein are methods for treating cancer in a subject in need thereof by administering chloroquine, or a salt or prodrug thereof, optionally with another agent that promotes Par-4 production to induce prostate apoptosis response-4 (Par-4) production by host cells, particularly non-cancerous host cells, to promote apoptosis in cancer cells, including androgen insensitive prostate cancer cells.
Assignees
The University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
15/576,366
Filing Date
6-1-2016
Recommended Citation
Rangnekar, Vivek M., "Chloroquine Induction Par-4 and Treatment of Cancer" (2019). Radiation Medicine Faculty Patents. 2.
https://uknowledge.uky.edu/radmed_patents/2