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Author ORCID Identifier

https://orcid.org/0000-0003-0476-086X

Date Available

9-1-2026

Year of Publication

2026

Document Type

Doctoral Dissertation

Degree Name

Doctor of Philosophy (PhD)

College

Arts and Sciences

Department/School/Program

Psychology

Faculty

Mark Fillmore

Faculty

Michael Bardo

Abstract

Growing evidence indicates that risky behavior among women is elevated during the late follicular phase of the menstrual cycle, likely due to increased estradiol levels. Furthermore, alcohol-induced impairment of women’s inhibitory control is significantly greater during the late versus early follicular phase. Consequently, cycle phase may influence outcomes of poor inhibitory control while intoxicated, such as alcohol-impaired driving. Alcohol-impaired driving risk manifests in two ways: risk-taking while driving, and risk awareness regarding the decision to drive. This dissertation tested the hypothesis that alcohol-induced increases in driver risk-taking and decreases in risk awareness would be exacerbated during the late versus early phase. Thirty-seven women ages 21-35 participated in a placebo-controlled study examining the effect of 0.60 g/kg alcohol on disinhibition, simulated driving performance, and self-reported risk awareness. Measures were obtained following placebo and alcohol during the early and late follicular phases. Alcohol increased driver risk-taking and impaired skill. Individual differences in alcohol-impaired driving were associated with behavioral and subjective measures in a phase-dependent manner. Late phase disinhibition under alcohol generally predicted driver risk-taking. Risk awareness predicted driver skill and driver risk-taking, during only the early phase. These findings advance understanding of risk factors associated with alcohol-impaired driving unique to women.

Digital Object Identifier (DOI)

https://doi.org/10.13023/etd.2026.27

Archival?

Archival

Funding Information

This work was supported by the National Institute on Alcohol Abuse and Alcoholism grant numbers R01 AA027990 (2021-2026) and T32 AA027488 (2022-2024).

Available for download on Tuesday, September 01, 2026

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