The Hypoviridae, comprising one genus, Hypovirus, is a family of capsidless viruses with positive-sense, ssRNA genomes of 9.1–12.7 kb that possess either a single large ORF or two ORFs. The ORFs appear to be translated from genomic RNA by non-canonical mechanisms, i.e. internal ribosome entry site-mediated and stop/restart translation. Hypoviruses have been detected in ascomycetous or basidiomycetous filamentous fungi, and are considered to be replicated in host Golgi-derived, lipid vesicles that contain their dsRNA as a replicative form. Some hypoviruses induce hypovirulence to host fungi, while others do not. This is a summary of the current ICTV report on the taxonomy of the Hypoviridae, which is available at www.ictv.global/report/hypoviridae.

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Published in Journal of General Virology, v. 99, issue 5, p. 615-616.

This is an open access article published by the Microbiology Society under the Creative Commons Attribution License.

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Production of this summary, the online chapter and associated resources was funded by a grant from the Wellcome Trust (WT108418AIA).

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Full ICTV Online (10th) Report: www.ictv.global/report/hypoviridae