Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases–Sponsored Expert Panel

Authors

• Alkis Togias, National Institute of Allergy and Infectious Diseases
• Susan F. Cooper, National Institute of Allergy and Infectious Diseases
• Maria L. Acebal, Food Allergy Research & Education
• Amal Assa'ad, University of Cincinnati
• James R. Baker, University of Michigan - Ann Arbor
• Lisa A. Beck, University of Rochester
• Julie Block, National Eczema Association
• Carol Byrd-Bredbenner, Rutgers University, Canada
• Edmond S. Chan, University of British Columbia, Canada
• Lawrence F. Eichenfield, University of California - San Diego
• David M Fleischer, University of Colorado - Denver
• George J. Fuchs III, University of KentuckyFollow
• Glenn T. Furuta, University of Colorado - Denver
• Matthew J. Greenhawt, University of Colorado - Denver
• Ruchi S. Gupta, Northwestern University
• Michele Habich, Central DuPage Hospital
• Stacie M. Jones, University of Arkansas at Little Rock
• Kari Keaton, Metro DC Food Allergy Support Group
• Antonella Muraro, Padua University, Italy
• Marshall Plaut, National Institute of Allergy and Infectious Diseases
• Lanny J. Rosenwasser, University of Missouri - Kansas City
• Daniel Rotrosen, National Institute of Allergy and Infectious Diseases
• Hugh A. Sampson, Harvard University
• Lynda C. Schneider, Boston Children’s Hospital
• Scott H. Sicherer, Icahn School of Medicine at Mount Sinai
• Robert Sidbury, University of Washington
• Jonathan Spergel, University of Pennsylvania
• David R. Stukus, Ohio State University
• Carina Venter, Cincinnati Children’s Hospital
• Joshua A. Boyce, Harvard University

Abstract

Background: Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institute of Allergy and Infectious Diseases, working with other organizations and advocacy groups, led the development of the first clinical guidelines for the diagnosis and management of food allergy. A recent landmark clinical trial and other emerging data suggest that peanut allergy can be prevented through introduction of peanut-containing foods beginning in infancy.

Objectives: Prompted by these findings, along with 25 professional organizations, federal agencies, and patient advocacy groups, the National Institute of Allergy and Infectious Diseases facilitated development of addendum guidelines to specifically address the prevention of peanut allergy.

Results: The addendum provides 3 separate guidelines for infants at various risk levels for the development of peanut allergy and is intended for use by a wide variety of health care providers. Topics addressed include the definition of risk categories, appropriate use of testing (specific IgE measurement, skin prick tests, and oral food challenges), and the timing and approaches for introduction of peanut-containing foods in the health care provider’s office or at home. The addendum guidelines provide the background, rationale, and strength of evidence for each recommendation.

Conclusions: Guidelines have been developed for early introduction of peanut-containing foods into the diets of infants at various risk levels for peanut allergy.

Document Type

Article

Publication Date

1-6-2017

Notes/Citation Information

Published in World Allergy Organization Journal, v. 10, 1, p. 1-18.

© COPYRIGHT NOTICE. 2017

The article is a work of the United States Government; Title 17 U.S.C 105 provides that copyright protection is not available for any work of the United States government in the United States. Additionally, this is an open access article distributed under the terms of the Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0), which permits worldwide unrestricted use, distribution, and reproduction in any medium for any lawful purpose.

Digital Object Identifier (DOI)

https://doi.org/10.1186/s40413-016-0137-9

Repository Citation

Togias, Alkis; Cooper, Susan F.; Acebal, Maria L.; Assa'ad, Amal; Baker, James R.; Beck, Lisa A.; Block, Julie; Byrd-Bredbenner, Carol; Chan, Edmond S.; Eichenfield, Lawrence F.; Fleischer, David M; Fuchs, George J. III; Furuta, Glenn T.; Greenhawt, Matthew J.; Gupta, Ruchi S.; Habich, Michele; Jones, Stacie M.; Keaton, Kari; Muraro, Antonella; Plaut, Marshall; Rosenwasser, Lanny J.; Rotrosen, Daniel; Sampson, Hugh A.; Schneider, Lynda C.; Sicherer, Scott H.; Sidbury, Robert; Spergel, Jonathan; Stukus, David R.; Venter, Carina; and Boyce, Joshua A., "Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases–Sponsored Expert Panel" (2017). Pediatrics Faculty Publications. 221.
https://uknowledge.uky.edu/pediatrics_facpub/221