US Patent Number
7705119
Publication Date
4-27-2010
Abstract
Polypeptides, compositions, and methods for treating shock are described. A isolated polypeptide, Deltorphin-E, can be administered without concomitant fluid resuscitation, before, concurrently with, or after the onset of shock or the occurrence of an event that creates a risk of shock. Deltorphin-E can be administered in accordance with the method as part of a preconditioning strategy, which reduces the extent of ischemic injury. Deltorphin-E can be used in preparation for planned ischemia or in a prophylactic manner in anticipation of further ischemic events.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
11/759,013
Filing Date
06/06/2007
Recommended Citation
Oeltgen, Peter R. and Govindaswami, Meera, "Compositions and Methods Useful for Treating Circulatory and Hypovolemic Shock" (2010). Pathology and Laboratory Medicine Faculty Patents. 1.
https://uknowledge.uky.edu/pathology_patents/1
