Archived
This content is available here strictly for research, reference, and/or recordkeeping and as such it may not be fully accessible. If you work or study at University of Kentucky and would like to request an accessible version, please use the SensusAccess Document Converter.
US Patent Number
8957035
Publication Date
2-17-2015
Abstract
Provided are methods and compositions for the treatment or prevention of ocular angiogenesis and neovascularization. Administration of stimulators of the TLR3 and TLR7 receptors, Trif or of IL-10 and IL-12 inhibits ocular angiogenesis. Furthermore, all siRNAs (both targeted and non-targeted) can inhibit ocular angiogenesis.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
12/304,450
Primary Class
05/15/2007
Recommended Citation
Ambati, Jayakrishna, "Toll like Receptor (TLR) Stimulation for Ocular Angiogenesis and Macular Degeneration" (2015). Ophthalmology and Visual Science Faculty Patents. 10.
https://uknowledge.uky.edu/ophthalmology_patents/10
