Abstract
The unique intricacies of ovarian cancer screening and perspectives of different screening methods are presented as ten considerations that are examined. Included in these considerations are: (1) Deciding on the number of individuals to be screened; (2) Anticipating screening group reductions due to death; (3) Deciding on the duration and frequency of screening; (4) Deciding on an appropriate follow-up period after screening; (5) Deciding on time to surgery when malignancy is suspected; (6) Deciding on how screen-detected ovarian cancers are treated and by whom; (7) Deciding on how to treat the data of enrolled participants; (8) Deciding on the most appropriate way to assign disease-specific death; (9) Deciding how to avoid biases caused by enrollments that attract participants with late-stage disease who are either symptomatic or disposed by factors that are genetic, environmental or social; and (10) Deciding whether the screening tool or a screening process is being tested. These considerations are presented in depth along with illustrations of how they impact the outcomes of ovarian cancer screening. The considerations presented provide alternative explanations of effects that have an important bearing on interpreting ovarian screening outcomes.
Document Type
Review
Publication Date
4-13-2017
Digital Object Identifier (DOI)
https://doi.org/10.3390/diagnostics7020022
Repository Citation
Pavlik, Edward J., "Ten Important Considerations for Ovarian Cancer Screening" (2017). Obstetrics and Gynecology Faculty Publications. 17.
https://uknowledge.uky.edu/obgyn_facpub/17
Included in
Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons, Obstetrics and Gynecology Commons
Notes/Citation Information
Published in Diagnostics, v. 7, issue 2, 22, p. 1-11.
© 2017 by the author. Licensee MDPI, Basel, Switzerland.
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).