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Hypercoagulable and Autoimmune Factors in Patients with Moyamoya Syndrome
Moyamoya is a progressive cerebrovascular condition leading to stenosis of the internal carotid arteries (ICA) and formation of abnormal vasculature at the base of the brain. Patients ultimately suffer from ischemic and/or hemorrhagic stroke. In Kentucky, patients often present with comorbidities, which classifies them as having moyamoya syndrome (MMS). In this prospective observational study, we measured coagulable- and autoimmune-related factors in MMS subjects to identify possible therapeutic targets and help inform clinical care. Venous blood samples were collected from adult subjects diagnosed with MMS and analyzed by the UK Healthcare Clinical Laboratory. Blood samples, demographics, and medical records were obtained ...Read More
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Single Nucleus RNA Sequencing of Human Sural Nerve Injury
Single nucleus RNA sequencing of human sural nerve injury collected from two participants at A proteomic analysis, using mass spectrometry and immunoassays, of the human peripheral nervous system's response to a transection injury. We obtained, from the same participants, the protein levels in freshly cut and degenerating human sural nerve tissue.
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Proteomic Analysis of Human Sural Nerve
A proteomic analysis, using mass spectrometry and immunoassays, of the human peripheral nervous system's response to a transection injury. We obtained, from the same participants, the protein levels in freshly cut and degenerating human sural nerve tissue.
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