Downbeat nystagmus is a type of jerk nystagmus that may be seen in patients with lesions affecting the vestibulocerebellum. This is a case of a 7-year-old girl presenting with a history of fever, headache, and episodic vertigo with downbeat nystagmus. The diagnosis of Epstein-Barr virus meningitis with acute cerebellitis was made by contrast magnetic resonance imaging, cerebrospinal fluid analysis, and serum Epstein-Barr virus titers. Contrast magnetic resonance imaging demonstrated enhancement of the meninges and inferior cerebellar folia, correlating with the neuroophthalmological symptom of downbeat nystagmus.
Digital Object Identifier (DOI)
Wade, Cameron A.; Toupin, David Neil; Darpel, Kyle; Jones, Kimberly S.; and Lightner, Donita D., "Downbeat Nystagmus in a 7-Year-Old Girl with Epstein-Barr Virus-Associated Meningitis and Cerebellitis" (2021). Neurology Faculty Publications. 80.