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US Patent Number

5977315

Publication Date

11-2-1999

Abstract

The present invention provides a monoclonal anti-idiotype antibody 3H1 that escapes immune tolerance and elicits a specific immune response to CEA in mice, rabbits, monkeys, and patients with advanced CEA-associated disease. This invention also provides compositions which can be used in the detection or treatment of CEA-associated tumors mimics a specific epitope on carcinoembryonic antigen and a hybridoma that produces 3H1.

Assignees

The Board of Trustees of the University of Kentucky, Lexington, Ky.

Application Number

08/579,940

Filing Date

12/28/1995

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