Cytisine-Linked Isoflavonoid Antineoplastic Agents for the Treatment of Cancer

Authors

Chunming Liu, University of KentuckyFollow
David S. Watt, University of KentuckyFollow
Mykhaylo S. Frasinyuk
Vitaliy M. Sviripa, University of KentuckyFollow
Wen Zhang, University of KentuckyFollow
Svitlana P. Bondarenko

US Patent Number

10,188,743

Publication Date

1-29-2019

Abstract

Cytisine-linked isoflavonoids, or pharmaceutically acceptable salts thereof or pharmaceutically acceptable compositions thereof, are useful for the treatment of conditions in which cells have a reliance on peroxisomal HSD17B4 to degrade very long chain fatty acids and provide necessary energy for cell proliferation, such as is seen in colorectal cancer and prostate cancer, for example.

Assignees

University of Kentucky Research Foundation, Lexington, KY (US)

Application Number

15/714,647

Filing Date

09/25/2017

Recommended Citation

Liu, Chunming; Watt, David S.; Frasinyuk, Mykhaylo S.; Sviripa, Vitaliy M.; Zhang, Wen; and Bondarenko, Svitlana P., "Cytisine-Linked Isoflavonoid Antineoplastic Agents for the Treatment of Cancer" (2019). Markey Cancer Center Faculty Patents. 5.
https://uknowledge.uky.edu/markey_patents/5