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Publication Date

1993

Location

New Zealand

Description

To test pathogenicity and mutagenicity of Gynaepllora ruoergensis nuclear polyhedrosis virus (GrNPV), a new biological pesticide, acute and subacute infection tests were carried out in 366 vertebrates (16 species). Results indicated that GrNPV has no toxicity to vertebrates. No mutagenicity to Salmonela. typhimium . was found using the Ames.test. Four tests using cytogenelic methods, sister chromosome exchange (SCB), chromosome aberration test, a micro-nuclear test of mouse eosinophH cells, and lethal effect tests, indicated no mutagenictic effects to vertebrates.

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Studies on the Mutagenicity of Gynaephora ruoergensis Nuclear Polyhedrosis Virus (GrNPV), a New Biological Pesticide

New Zealand

To test pathogenicity and mutagenicity of Gynaepllora ruoergensis nuclear polyhedrosis virus (GrNPV), a new biological pesticide, acute and subacute infection tests were carried out in 366 vertebrates (16 species). Results indicated that GrNPV has no toxicity to vertebrates. No mutagenicity to Salmonela. typhimium . was found using the Ames.test. Four tests using cytogenelic methods, sister chromosome exchange (SCB), chromosome aberration test, a micro-nuclear test of mouse eosinophH cells, and lethal effect tests, indicated no mutagenictic effects to vertebrates.