Human Peripheral Nerve Injury Research Data

Follow

• 

  Single Nucleus RNA Sequencing of Human Sural Nerve Injury

  Single nucleus RNA sequencing of human sural nerve injury collected from two participants at A proteomic analysis, using mass spectrometry and immunoassays, of the human peripheral nervous system's response to a transection injury. We obtained, from the same participants, the protein levels in freshly cut and degenerating human sural nerve tissue.

  Please use the downloadable form to request data access by email.

• 

  Proteomic Analysis of Human Sural Nerve

  A proteomic analysis, using mass spectrometry and immunoassays, of the human peripheral nervous system's response to a transection injury. We obtained, from the same participants, the protein levels in freshly cut and degenerating human sural nerve tissue.

• 

  RNA Sequencing of Human Peripheral Nerve in Response to Injury: Distinctive Analysis of the Nerve Repair Pathways

  The development of regenerative therapies for central nervous system diseases can likely benefit from an understanding of the peripheral nervous system repair process, particularly in identifying potential gene pathways involved in human nerve repair. This study employed RNA sequencing (RNA-seq) technology to analyze the whole transcriptome profile of the human peripheral nerve in response to an injury. The distal sural nerve was exposed, completely transected, and a 1 to 2 cm section of nerve fascicles was collected for RNA-seq from six participants with Parkinson's disease, ranging in age between 53 and 70 yr. Two weeks after the initial injury, another ...Read More