A high-passage rabbit kidney RK-13 cell line (HP-RK-13[KY], originally derived from the ATCC CCL-37 cell line) used in certain laboratories worldwide is contaminated with noncytopathic bovine viral diarrhea virus (ncpBVDV). On complete genome sequence analysis, the virus strain was found to belong to BVDV group 1b.
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This study was supported by the Agriculture and Food Research Initiative competitive grant no. 2013-68004-20360 from the United States Department of Agriculture National Institute of Food and Agriculture (USDA-NIFA).
Nam, Bora; Li, Ganwu; Zheng, Ying; Zhang, Jianqiang; Shuck, Kathleen M.; Timoney, Peter J.; and Balasuriya, Udeni B. R., "Complete Genome Sequence of Noncytopathic Bovine Viral Diarrhea Virus 1 Contaminating a High-Passage RK-13 Cell Line" (2015). Maxwell H. Gluck Equine Research Center Faculty Publications. 3.