CRVAW Faculty Journal Articles
Abstract
Background
This study aimed to address long-term survival in a large population-based cohort of men with prostate cancer receiving radical prostatectomy compared to other treatments.
Methods
We studied 5,845 patients diagnosed with local/regional stage prostate cancer at age 65–74 in 1992 with comorbidity score
Results
Of 5,845 patients, 10-year all-cause survival rates were the highest for patients receiving radical prostatectomy (81.0%; 95% CI: 79.4–82.4%), followed by radical prostatectomy in combination with radiotherapy (67.6%; 62.0–72.5%), radiotherapy (60.5%; 58.3–62.6%), and were the lowest for watchful-waiting (50.7%; 47.5–53.8%). A similar pattern was found for 10-year prostate cancer-specific survivals by treatments. After adjusting for age, ethnicity, region, Gleason Score, comorbidity, median annual household income, hormone therapy and chemotherapy, the hazard ratio of all-cause mortality was 0.31 (95% CI: 0.25–0.37) for radical prostatectomy and 0.38 (95% CI: 0.28–0.52) for radical prostatectomy plus radiation therapy compared to those with watchful-waiting.
Conclusions
There was a significant long-term survival benefit in men receiving radical prostatectomy compared to those receiving watchful-waiting or radiotherapy. J. Surg. Oncol. 2008;97:583–591. © 2008 Wiley-Liss, Inc.
Document Type
Article
Publication Date
6-1-2008
Digital Object Identifier (DOI)
http://dx.doi.org/10.1002/jso.21028
Repository Citation
Liu, Liqian; Coker, Ann L.; Du, Xianglin L.; Cormier, Janice N.; Ford, Charles E.; and Fang, Shenying, "Long-Term Survival After Radical Prostatectomy Compared to Other Treatments in Older Men With Local or Regional Prostate Cancer" (2008). CRVAW Faculty Journal Articles. 102.
https://uknowledge.uky.edu/crvaw_facpub/102
Notes/Citation Information
Published in Journal of Surgical Oncology, v. 97, no. 7, p. 583-591.