Year of Publication

2016

College

Public Health

Date Available

5-3-2016

Degree Name

Master of Public Health (M.P.H.)

Committee Chair

David Mannino, MD

Committee Member

Sabrina Brown, DrPH, MPH

Committee Member

W. Jay Christian, PhD

Abstract

Objective

The objective of the study is to compare the Non-Cystic Fibrosis Bronchiectasis patients with Non Tubercular Mycobacteria (NTM) and Non-NTM infection and determine if the NTM and Non-NTM groups are different.

Methods

Data from the COPD Foundation’s Bronchiectasis Research Registry (BRR) was used in the study (n=1660).Logistic regression, Cox proportional hazards regression, and Kaplan Meier survival analysis were used to analyze the data.

Results

The study found odds ratio for having NTM infection for age to be 1.02 and for gender to be 2.34, after adjusting for all other variables in the multivariate logistic regression, with the p-value of

Conclusion

This study, one of the first study done using the BRR’s database found age and gender to be significantly associated with NTM infection, but did not found any difference in survival among patients of the two groups. Further studies need to be done to expand the horizon of this less researched topic.

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