Date Available

4-28-2022

Year of Publication

2022

Document Type

Graduate Capstone Project

Degree Name

Master of Public Health (M.P.H.)

College

Public Health

Faculty

Thomas Tucker

Faculty

Sarah Wackerbarth

Faculty

Jaclyn McDowell

Abstract

OBJECTIVE: This population-based retrospective cohort study examines the association of sociodemographic disparities with the receipt of chemotherapy among patients with metastatic non-small cell lung cancer in the Commonwealth of Kentucky in the precision oncology and immunotherapy era.

METHODS: Kentucky Cancer Registry data from 2010 through 2017 was analyzed using univariate, bivariate, unadjusted, and adjusted multivariate regressions to assess disparities in our population (N = 9490).

RESULTS:We found no significant difference in receipt of chemotherapy between sexes (OR 0.99, P=0.90) nor races (OR 1.12, P=0.22). Patients diagnosed in an Appalachia county were significantly less likely to receive chemotherapy (OR 0.71, P

Patients who were married or lived with a domestic partner were significantly more likely to receive chemotherapy (OR 1.71, P

CONCLUSIONS: Higher proportions of patients have received chemotherapy over time. Receipt of life-prolonging chemotherapy is associated with patients’ age, Appalachian status, marital/living status, insurance type, and tobacco use.

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