Abstract

An in vitro model of bacterial biofilms on rigid gas-permeable contact lenses (RGPLs) was developed to challenge oral epithelial cells. This novel model provided seminal data on oral biofilm-host cell interactions, and with selected bacteria, the biofilms were more effective than their planktonic counterparts at stimulating host cell responses.

Document Type

Article

Publication Date

10-2011

Notes/Citation Information

Published in Clinical and Vaccine Immunology, v. 18, no. 10, p. 1770–1772.

Copyright © 2011, American Society for Microbiology. All Rights Reserved.

The copyright holders have granted the permission for posting the article here.

Digital Object Identifier (DOI)

http://dx.doi.org/10.1128/CVI.05162-11

Funding Information

This work was supported by USPHS grant R21 DE018177 from the National Institute for Dental and Craniofacial Research.

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