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US Patent Number

8580240

Publication Date

11-12-2013

Abstract

Compounds and methods for reducing the occurrence of a post-surgical adhesion are provided. The compounds can include acrylic acid groups and ethylene glycol groups, and can be directed to an area of damaged tissue by the incorporation of a fibrin targeting peptide. The compounds can further include a brush-like portion, capable of creating a steric barrier between a damaged tissue or organ and adjacent tissues or organs, and a targeting portion, capable of directing the compounds to a damaged tissue or organ. Methods of detecting damaged tissue and kits are also provided.

Assignees

University of Kentucky Research Foundation, Lexington, KY (US)

Application Number

12/622,239

Filing Date

11/19/2009

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