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US Patent Number

5272055

Publication Date

12-21-1993

Abstract

A method for diagnosing a neurological disease comprising detecting a neurological disease-specific biochemical marker macromolecule within a sample of extracted cerebral spinal fluid is disclosed. In particular, a radioactively labeled photoaffinity probe is used to diagnose a neurological disease. For instance, Alzheimer's disease can be diagnosed by detecting a disease-specific protein having a molecular weight of about 42,000 daltons, i.e., glutamine synthetase.

Assignees

University of Kentucky Research Foundation, Lexington, Ky.

Application Number

812,826

Filing Date

12/24/1991

Included in

Chemistry Commons

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