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US Patent Number
5596081
Publication Date
1-21-1997
Abstract
Sites on antibodies having affinity for photoaffinity compounds, in particular purine or azidopurine containing compounds are taught. These sites provide for the site-specific attachment of nucleotide photoaffinity compounds to antibodies, e.g., ATP- or GTP-analog photoaffinity compounds by photochemical reaction. These nucleotide photoaffinity compounds may additionally be attached to molecules having a desired therapeutic or diagnostic activity, and the resultant conjugates used as diagnostics or therapeutics.
Assignees
University of Kentucky Research Foundation, Lexington, Ky.
Application Number
208,822
Filing Date
03/11/1994
Recommended Citation
Haley, Boyd E.; Köhler, Heinz; Rajagopalan, Krishnan; and Pavlinkova, Gabriela, "Nucleotide or Nucleoside Photoaffinity Compound Modified Antibodies, Methods for Their Manufacture and Use Thereof as Diagnostics and Therapeutics" (1997). Chemistry Faculty Patents. 31.
https://uknowledge.uky.edu/chemistry_patents/31
