Abstract
Radiation therapy is one of the most prevalent procedures for cancer treatment, but the risks of malignancies induced by peripheral beam in healthy tissues surrounding the target is high. Therefore, being able to accurately measure the exposure dose is a critical aspect of patient care. Here a radiation detector based on an organic field‐effect transistor (RAD‐OFET) is introduced, an in vivo dosimeter that can be placed directly on a patient's skin to validate in real time the dose being delivered and ensure that for nearby regions an acceptable level of low dose is being received. This device reduces the errors faced by current technologies in approximating the dose profile in a patient's body, is sensitive for doses relevant to radiation treatment procedures, and robust when incorporated into conformal large‐area electronics. A model is proposed to describe the operation of RAD‐OFETs, based on the interplay between charge photogeneration and trapping.
Document Type
Article
Publication Date
9-23-2020
Digital Object Identifier (DOI)
https://doi.org/10.1002/advs.202001522
Funding Information
The device characterization was performed with support from grants from the National Science Foundation through Grants DMR-1627925 and ECCS- 1810273. The organic semiconductors used in this work were prepared with support from the National Science Foundation under Cooperative Agreement No. 1849213.
Repository Citation
Zeidell, Andrew M.; Ren, Tong; Filston, David S.; Iqbal, Hamna F.; Holland, Emma; Bourland, J. Daniel; Anthony, John E.; and Jurchescu, Oana D., "Organic Field-Effect Transistors as Flexible, Tissue-Equivalent Radiation Dosimeters in Medical Applications" (2020). Chemistry Faculty Publications. 167.
https://uknowledge.uky.edu/chemistry_facpub/167
Supporting Information
Notes/Citation Information
Published in Advanced Science, v. 7, issue 18, 2001522.
© 2020 The Authors
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.