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US Patent Number
9433638
Publication Date
9-6-2016
Abstract
The presently-disclosed subject matter includes compounds that comprise an initiator and an active agent that is covalently bonded to the initiator through a ring-opening polymerization process, an atom-transfer radical polymerization process, a Michael addition reaction, or a ring-opening metathesis polymerization process. In some embodiments the active agent includes simvastatin. The presently-disclosed subject matter also includes methods for making the compositions and methods for using the compositions to treat tissue wounds.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
14/505,381
Filing Date
10/02/2014
Recommended Citation
Puleo, David A.; Dziubla, Thomas D.; and Asafo-Adjei, Theodora, "Polymeric Prodrug" (2016). Biomedical Engineering Faculty Patents. 13.
https://uknowledge.uky.edu/cbme_patents/13
