Arylquinoline and Analog Compounds and Use Thereof to Treat Cancer

Authors

David S. Watt, University of KentuckyFollow
Chunming Liu, University of KentuckyFollow
Vivek M. Rangnekar, University of KentuckyFollow
Vitaliy M. Sviripa, University of KentuckyFollow
Ravshan Burikhanov, University of KentuckyFollow
Wen Zhang, University of KentuckyFollow

US Patent Number

9,873,670

Publication Date

1-23-2018

Abstract

The subject technology relates to arylquinoline compounds and their use for treating cancer or cancer metastasis. The compounds of the subject technology promote cells to secrete a pro-apoptotic tumor suppressor, i.e., prostate apoptosis response-4 (Par-4), which in turn promote apoptosis in cancer cells or metastatic cells.

Assignees

University of Kentucky Research Foundation, Lexington, KY (US)

Application Number

15/036,916

Filing Date

11/21/2014

Recommended Citation

Watt, David S.; Liu, Chunming; Rangnekar, Vivek M.; Sviripa, Vitaliy M.; Burikhanov, Ravshan; and Zhang, Wen, "Arylquinoline and Analog Compounds and Use Thereof to Treat Cancer" (2018). Molecular and Cellular Biochemistry Faculty Patents. 25.
https://uknowledge.uky.edu/biochem_patents/25