Abstract
The family Rhabdoviridae consists of mostly enveloped, bullet-shaped or bacilliform viruses with a negative-sense, single-stranded RNA genome that infect vertebrates, invertebrates or plants. This ecological diversity is reflected by the diversity and complexity of their genomes. Five canonical structural protein genes are conserved in all rhabdoviruses, but may be overprinted, overlapped or interspersed with several novel and diverse accessory genes. This review gives an overview of the characteristics and diversity of rhabdoviruses, their taxonomic classification, replication mechanism, properties of classical rhabdoviruses such as rabies virus and rhabdoviruses with complex genomes, rhabdoviruses infecting aquatic species, and plant rhabdoviruses with both mono- and bipartite genomes.
Document Type
Review
Publication Date
1-2-2017
Digital Object Identifier (DOI)
https://doi.org/10.1016/j.virusres.2016.10.010
Funding Information
Author contributions were also supported in part by the International Collaboration Research Program on Joint Usage/Research Center Program at the IPSR, Okayama University and by a grant from the National Institutes of Health R24AI120942 to NV.
Repository Citation
Dietzgen, Ralf G.; Kondo, Hideki; Goodin, Michael M.; Kurath, Gael; and Vasilakis, Nikos, "The Family Rhabdoviridae: Mono- and Bipartite Negative-Sense RNA Viruses with Diverse Genome Organization and Common Evolutionary Origins" (2017). Plant Pathology Faculty Publications. 89.
https://uknowledge.uky.edu/plantpath_facpub/89
Notes/Citation Information
Published in Virus Research, v. 227, p. 158-170.
© 2016 Elsevier B.V. All rights reserved.
This manuscript version is made available under the CC‐BY‐NC‐ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/.
The document available for download is the author's post-peer-review final draft of the article.