US Patent Number
Compounds and methods for reducing the occurrence of a post-surgical adhesion are provided. The compounds can include acrylic acid groups and ethylene glycol groups, and can be directed to an area of damaged tissue by the incorporation of a fibrin targeting peptide. The compounds can further include a brush-like portion, capable of creating a steric barrier between a damaged tissue or organ and adjacent tissues or organs, and a targeting portion, capable of directing the compounds to a damaged tissue or organ. Methods of detecting damaged tissue and kits are also provided.
University of Kentucky Research Foundation, Lexington, KY (US)
Dziubla, Thomas; Kaplan, Eugene; and Medley, John Mark Jr., "Compounds and Methods for Reducing the Occurrence of Post-Surgical Adhesions" (2013). Chemical and Materials Engineering Faculty Patents. Paper 3.