Innovative Computational Methods for Pharmaceutical Problem Solving a Review Part I: The Drug Development Process
Computational methods have provided pharmaceutical scientists and engineers a means to go beyond what's possible with experimental testing alone. Providing a means to study active pharmaceutical ingredients (API), excipients, and drug interactions at or near-atomic levels. This paper provides a review of this and other innovative computational methods used for solving pharmaceutical problems throughout the drug development process. Part one of two this paper will emphasize the role of computational methods and game theory in solving pharmaceutical challenges.
The work described was supported in part by the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health, through Grant UL1TR001998, and through NSF ACI-1053575 allocation number BIO170011. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. We also acknowledge the support of the University of Kentucky Department of Pharmaceutical Sciences.
Campbell, Heather R. and Lodder, Robert A., "Innovative Computational Methods for Pharmaceutical Problem Solving a Review Part I: The Drug Development Process" (2021). Pharmaceutical Sciences Faculty Publications. 169.
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