Year of Publication

2013

Degree Name

Doctor of Philosophy (PhD)

Document Type

Doctoral Dissertation

College

Arts and Sciences

Department

Physics and Astronomy

First Advisor

Dr. Janelle A. Molloy

Abstract

A patient specific image planning system (IPS) was developed that can be used to assist in kV imaging technique selection during localization for radiotherapy. The IPS algorithm performs a divergent ray-trace through a three dimensional computed tomography (CT) data set. Energy-specific attenuation through each voxel of the CT data set is calculated and imaging detector response is integrated into the algorithm to determine the absolute values of pixel intensity and image contrast. Phantom testing demonstrated that image contrast resulting from under exposure, over exposure as well as a contrast plateau can be predicted by use of a prospective image planning algorithm. Phantom data suggest the potential for reducing imaging dose by selecting a high kVp without loss of image contrast. In the clinic, image acquisition parameters can be predicted using the IPS that reduce patient dose without loss of useful image contrast.

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