US Patent Number
The present invention relates to methods for protecting against damage caused by radiation and/or chemotherapy, and methods for treating bone marrow damage by reducing/ inhibiting Latexin expression and/or Latexin activity. The methods comprise administering to a subject in need thereof a pharmaceutical composition comprising an antagonist that reduces expression and/or activity of latexin, wherein latexin is a latexin polynucleotide variant and/or a latexin polypeptide variant that binds to the antagonist.
University of Kentucky Research Foundation, Lexington, KY (US)
Van Zant, Gary; Liang, Ying; and Liu, Yi, "Protection against Ionizing Radiation and Chemotherapy Toxicity via Latexin Regulation" (2020). Internal Medicine Faculty Patents. 11.