Abstract
Syphilis hepatitis is a rare cause of acute liver injury. Primary biliary cholangitis (PBC) is a progressive autoimmune disease characterized by the typical presentation of a cholestatic liver injury and the presence of antimitochondrial antibodies (AMAs). We present a case of syphilis hepatitis that presented as a mimic to PBC with positive AMA. The eradication of syphilis led to the resolution of the liver injury and down trending of the antibody level. We recommend excluding syphilis in patients with high-risk behaviors presenting with a cholestatic liver injury and positive AMA before the diagnosis of PBC.
Document Type
Article
Publication Date
12-2020
Digital Object Identifier (DOI)
https://doi.org/10.14309/crj.0000000000000497
Repository Citation
Kern, Cody; Elmoursi, Ahmed; Blake, Caroline; and Hoellein, Andrew, "Syphilis Hepatitis Presenting as a Mimic of Primary Biliary Cholangitis" (2020). Internal Medicine Faculty Publications. 223.
https://uknowledge.uky.edu/internalmedicine_facpub/223
Notes/Citation Information
Published in ACG Case Reports Journal, v. 7, issue 12, e00497.
© 2020 The Author(s)
This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.