Theses and Dissertations--Chemistry, University of Kentucky | Chemistry | University of Kentucky

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Theses and Dissertations--Chemistry

Theses/Dissertations from 2022 2022

MECHANISM OF ANTIBIOTIC PERMEABILITY THROUGH THE GRAM-NEGATIVE BACTERIAL ENVELOPE, Olaniyi Alegun

THE DESIGN AND SYNTHESIS OF NEW ORGANIC DITHIOLS FOR ENVIRONMENTAL APPLICATIONS, Shashika Nadishani Bandara

Structural basis of bacterial flagellin for NAIP5 binding and NLRC4 inflammasome activation and the mechanism of flagellin induced release of cytokines in vivo, Jian Cui

MASS SPECTROMETRIC ANALYSIS OF LIGNIN MODEL COMPOUNDS: FUNDAMENTAL INVESTIGATIONS OF IONIZATION AND SUPRAMOLECULAR INTERACTIONS FOR LIGNOCELLULOSIC BIOMASS APPLICATIONS, Kimberly Dean

Crystal Engineering of Asymmetric and Pyrene Fused Annulenes for Use in Organic Electronic Materials, Garrett Fregoso

DEVELOPMENTS IN GOLD(III) SCAFFOLDS FOR PROTEIN BIOCONJUGATION AND ENHANCED ANTICANCER ACTIVITY, Sailajah Gukathasan

PHOTOCATALYTIC APPLICATIONS OF TiO₂ FOR CATECHOL DEGRADATION AND α-Fe₂O₃ FOR CARBON DIOXIDE REDUCTION AT AIR-SOLID INTERFACE, Md Ariful Hoque

SYNTHESIS OF 6,6- AND 7,7-DIFLUORO-1-ACETAMIDOPYRROLIZIDINES AND THEIR OXIDATION CATALYZED BY THE NONHEME Fe OXYGENASE LolO, Nabin Panth

Oxidative Damage to Brain Cells Underlies: (I) Resistance to Radiation and Increased Tumor Cell Growth in Glioblastoma; (II) ApoE Allele Status and Pentose Phosphate Pathway Proteins in Alzheimer Disease Mouse Models, Nicole Rummel

SUCCINYLATED POLYETHYLENIMINE GENE DELIVERY AGENTS FOR ENHANCED TRANSFECTION EFFICACY, Md. Nasir Uddin

SYNTHESIS AND IN SITU CHARACTERIZATION OF INTERCALATED TRANSITION METAL OXIDE NANOMATERIALS INVESTIGATED FOR NOVEL CATHODE APPLICATIONS, Ahamed Ullah

Theses/Dissertations from 2021 2021

ClpXP Degradation System in Escherichia coli, a Study of Its Energy Sources and Its Applications in Managing the Expression Levels of Targeted Membrane and Soluble Proteins, Thilini Abeywansha

COMPUTATIONAL INSIGHTS ON MEDICINAL CHEMISTRY TARGETING CYP450s, Alexander D. Fenton

Synthesis of Dual Small Molecule Hybrids to Probe the Synergy between DNA Repair Enzymes and IDO1, Nathaniel George

Synthesis, Crystal Engineering, and Material Properties of Small-Molecule Organic Semiconductors, Emma Holland

MASS SPECTROMETRY METHOD DEVELOPMENT FOR THE DISCOVERY AND CHARACTERIZATION OF SECONDARY METABOLITES, Zachary Kelley

PLASMON ENHANCED SINGLE MOLECULE FLUORESCENCE IN ZERO MODE WAVEGUIDES (ZMWS), Abdullah Masud

DEVELOPING SYNTHETIC STRATEGIES FOR MULTIFACETED APPLICATIONS OF STABLE GOLD-BASED COMPLEXES, Randall Tyler Mertens

Flavin Modification and Redox Tuning in the Bifurcating Electron Transfer Flavoprotein from Rhodopseudomonas palustris: Two Arginines with Different Roles, Nishya Mohamed-Raseek

UNDERSTANDING THE ROLE OF CHARGE ON PARTICLE TRANSPORT WITHIN SEMIDILUTE AND CONCENTRATED BIOPOLYMER SOLUTIONS AND TAU PROTEIN CONDENSATES, Kanthi Nuti

Rational Design of Small Molecule Disruptors of Protein-Protein Interactions: PD-1/PD-L1; c-MYC, ARID4B, Samuel Ofori

Probing the Assembly, Functional Relevance, and Dynamics of AcrA in Multi Drug Efflux in Escherichia coli, Isoiza Ojo

Investigation of Multidrug Efflux Transporter AcrB in Escherichia coli: Assembly, Degradation and Dynamics, Prasangi Irosha Rajapaksha

Determining Material Structures and Surface Chemistry by Genetic Algorithms and Quantum Chemical Simulations, Josiah Jesse Roberts

DESIGN, SYNTHESIS, AND ANTICANCER PROPERTIES OF Ru(II) COMPLEXES WITH ORGANOMETALLIC, “EXPANDED” BIPYRIDINE, AND O,O’-CHELATING LIGANDS, Raphael Ryan

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