Author ORCID Identifier
https://orcid.org/0009-0005-4351-2967
Date Available
5-1-2026
Year of Publication
2025
Document Type
Master's Thesis
Degree Name
Master of Science in Biomedical Engineering
College
Engineering
Department/School/Program
Biomedical Engineering
Faculty
Sheng Tong
Faculty
Sridhar Sunderam
Abstract
Magnetic heating mediated by magnetic iron oxide nanoparticles (MION) has several clinical applications including cancer thermal therapy, tissue thawing for organ preservation, and magnetogenetics. However, current models of magnetic heating, including the widely used linear response theory, inadequately predict MION heating efficiency. An experimental study covering alternating magnetic field (AMF) strengths and frequencies ranging from 3.98 – 27.85 kA/m and 103.6 – 984.1 kHz, respectively, with a range of MION core diameters 9.5- 30.3 nm was conducted to elucidate the relationships between these AMF parameters and MION sizes and the resulting heating efficiencies. Heating efficiency was found to increase approximately linearly with increases in frequency, field strength, and MION size in disagreement with calculated values estimated by the linear response theory. These findings highlight new considerations when selecting MIONs for magnetic heating applications and provide guidance in the development of future models of magnetic heating.
Digital Object Identifier (DOI)
https://doi.org/10.13023/etd.2025.22
Funding Information
This study was supported by a grant from the National Science Foundation (no.: 2342391) on understanding the nanoscale interactions in magnetogenetics in 2025.
Recommended Citation
Kubican, Sarah E., "Magnetic Heating Efficiency of Magnetite Nanoparticles: Dependence on Size and Alternating Magnetic Field" (2025). Theses and Dissertations--Biomedical Engineering. 84.
https://uknowledge.uky.edu/cbme_etds/84
Included in
Biomaterials Commons, Nanomedicine Commons, Other Biomedical Engineering and Bioengineering Commons
