BIVENTRICULAR FINITE ELEMENT MODELING AND QUANTIFICATION OF 3D LANGRAGIAN STRAINS AND TORSION USING DENSE MRI

Author

Zhanqiu Liu, University of KentuckyFollow

Date Available

4-28-2016

Year of Publication

2016

Degree Name

Master of Science in Mechanical Engineering (MSME)

Document Type

Master's Thesis

College

Engineering

Department/School/Program

Mechanical Engineering

First Advisor

Dr. Jonathan F. Wenk

Abstract

Statistical data suggests that increased use of evidence-based medical therapies has largely contributed to the decrease in American death rate caused by heart disease. And my studies are about two applications of magnetic resonance imaging (MRI) as a non-invasive approach in evidence-based health care research. In my first study, the achievement of a pulmonary valve replacement surgery was assessed on a patient with tetralogy of Fallot (TOF). In order to evaluate the remodeling of right ventricle, two biventricular finite element models were built up for pre-surgical images and post-surgical images. In my second study, 3D Lagrangian strains and torsion in the left ventricle of ten rats were investigated using Displacement ENcoding with Stimulated Echoes (DENSE) cardiac magnetic resonance (CMR) images. Tools written in MATLAB were developed for 2D contouring, 3D modeling, strain and torsion computations, and statistical comparison across subjects.

Digital Object Identifier (DOI)

http://dx.doi.org/10.13023/ETD.2016.187

Recommended Citation

Liu, Zhanqiu, "BIVENTRICULAR FINITE ELEMENT MODELING AND QUANTIFICATION OF 3D LANGRAGIAN STRAINS AND TORSION USING DENSE MRI" (2016). Theses and Dissertations--Mechanical Engineering. 80.
https://uknowledge.uky.edu/me_etds/80