Abstract

The title compound, C20H23N3O6·CH3OH, was synthesized by [3 + 2] cyclo­addition of (Z)-2,3-bis­(3,4,5-tri­meth­oxy­phen­yl)acrylo­nitrile with sodium azide and ammonium chloride in DMF/water. The central nitro­gen of the triazole ring is protonated. The dihedral angles between the triazole ring and the 3,4,5-tri­meth­oxy­phenyl ring planes are 34.31 (4) and 45.03 (5)°, while that between the 3,4,5-tri­meth­oxy­phenyl rings is 51.87 (5)°. In the crystal, the mol­ecules, along with two methanol solvent mol­ecules are linked into an R 4 4(10) centrosymmetric dimer by N—H⋯O and O—H⋯N hydrogen bonds.

Document Type

Article

Publication Date

10-2014

Notes/Citation Information

Published in Acta Crystallographica Section E Structure Reports Online, v. 70, no. 10, p. o1128-o1129.

Copyright © Madadi et al. 2014

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.

Digital Object Identifier (DOI)

http://dx.doi.org/10.1107/S1600536814020911

Funding Information

This investigation was supported NIH/National Cancer Institute (CA140409) United States, and we also thank the Arkansas Research Alliance for financial support.

Related Content

CCDC reference: 1025101

Additional supporting information: crystallographic information; 3D view; checkCIF report

e-70-o1128-sup1.cif (846 kB)
Crystal structure: contains datablock(s) global, I. DOI: 10.1107/S1600536814020911/sj5427sup1.cif

e-70-o1128-Isup2.hkl (267 kB)
Structure factors: contains datablock(s) I. DOI: 10.1107/S1600536814020911/sj5427Isup2.hkl

e-70-o1128-Isup3.cml (8 kB)
Supporting information file. DOI: 10.1107/S1600536814020911/sj5427Isup3.cml

e-70-o1128-fig1.tif (1357 kB)
A view of the asymmetric unit of the structure with the atom numbering scheme. Displacement ellipsoids are drawn at the 50% probability level and a hydrogen bond is drawn as a dashed line. DOI: 10.1107/S1600536814020911/sj5427fig1.tif

fig.pptx (789 kB)
Figure 1: A view of the asymmetric unit of the structure with the atom numbering scheme. Displacement ellipsoids are drawn at the 50% probability level and a hydrogen bond is drawn as a dashed line.

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