This collection was named as Graduate Center for Toxicology Faculty Publications before Jan. 1, 2015.

Follow


Submissions from 2018

PDF

GRP78 Is a Targetable Receptor on Cancer and Stromal Cells, Nathalia Araujo, Nikhil Hebbar, and Vivek M. Rangnekar

PDF

Acute Loss of Iron-Sulfur Clusters Results in Metabolic Reprogramming and Generation of Lipid Droplets in Mammalian Cells, Daniel R. Crooks, Nunziata Maio, Andrew N. Lane, Michal Jarnik, Richard M. Higashi, Ronald G. Haller, Ye Yang, Teresa Whei-Mei Fan, W. Marston Linehan, and Tracey A. Rouault

PDF

Stable Isotope-Resolved Metabolomics Shows Metabolic Resistance to Anti-Cancer Selenite in 3D Spheroids Versus 2D Cell Cultures, Teresa W. -M. Fan, Salim S. El-Amouri, Jessica K. A. Macedo, Qing Jun Wang, Huan Song, Teresa Cassel, and Andrew N. Lane

PDF

Beta-Catenin Cleavage Enhances Transcriptional Activation, Tatiana Goretsky, Emily M. Bradford, Qing Ye, Olivia F. Lamping, Tomas Vanagunas, Mary Pat Moyer, Patrick C. Keller, Preetika Sinh, Josep M. Llovet, Tianyan Gao, Qing-Bai She, Linheng Li, and Terrence A. Barrett

PDF

Sirtuin 1-Mediated Deacetylation of XPA DNA Repair Protein Enhances Its Interaction with ATR Protein and Promotes cAMP-Induced DNA Repair of UV Damage, Stuart G. Jarrett, Katharine M. Carter, Robert-Marlo Bautista, Daheng He, Chi Wang, and John A. D’Orazio

PDF

ALS Mutations of FUS Suppress Protein Translation and Disrupt the Regulation of Nonsense-Mediated Decay, Marisa Kamelgarn, Jing Chen, Lisha Kuang, Huan Jin, Edward J. Kasarskis, and Haining Zhu

PDF

Doxorubicin-Induced Elevated Oxidative Stress and Neurochemical Alterations in Brain and Cognitive Decline: Protection by MESNA and Insights into Mechanisms of Chemotherapy-Induced Cognitive Impairment ("Chemobrain"), Jeriel T. R. Keeney, Xiaojia Ren, Govind Warrier, Teresa Noel, David K. Powell, Jennifer M. Brelsfoard, Rukhsana Sultana, Kathryn E. Saatman, Daret K. St. Clair, and D. Allan Butterfield

PDF

Aged Murine Hematopoietic Stem Cells Drive Aging-Associate Immune Remodeling, Hanna Leins, Medhanie Mulaw, Karina Eiwen, Vadim Sakk, Ying Liang, Michael Denkinger, Hartmut Geiger, and Reinhold Schirmbeck

PDF

Glutathione de Novo Synthesis but Not Recycling Process Coordinates with Glutamine Catabolism to Control Redox Homeostasis and Directs Murine T Cell Differentiation, Gaojian Lian, J. N. Rashida Gnanaprakasam, Tingting Wang, Ruohan Wu, Xuyong Chen, Lingling Liu, Yuqing Shen, Mao Yang, Jun Yang, Ying Chen, Vasilis Vasiliou, Teresa A. Cassel, Douglas R. Green, Yusen Liu, Teresa W. -M. Fan, and Ruoning Wang

PDF

Nanoparticle-Mediated Therapeutic Agent Delivery for Treating Metastatic Breast Cancer—Challenges and Opportunities, Yunfei Li, Brock Humphries, Chengfeng Yang, and Zhishan Wang

PDF

MTBP Inhibits the Erk1/2-Elk-1 Signaling in Hepatocellular Carcinoma, Atul Ranjan, Swathi V. Iyer, Christopher Ward, Tim Link, Francisco J. Diaz, Animesh Dhar, Ossama W. Tawfik, Steven A. Weinman, Yoshiaki Azuma, Tadahide Izumi, and Tomoo Iwakuma

PDF

H3K9 Methyltransferases and Demethylases Control Lung Tumor-Propagating Cells and Lung Cancer Progression, S. P. Rowbotham, F Li, A. F. M. Dost, S. M. Louie, B. P. Marsh, P. Pessina, C. R. Anbarasu, Christine Fillmore Brainson, S. J. Tuminello, A. Lieberman, S. Ryeom, T. M. Schlaeger, B. J. Aronow, H. Watanabe, K. K. Wong, and C. F. Kim

PDF

Profiling Prostate Cancer Therapeutic Resistance, Cameron A. Wade and Natasha Kyprianou

PDF

Evaluating Disparities in the U.S. Technology Transfer Ecosystem to Improve Bench to Business Translation, James Weis, Ashvin Bashyam, Gregory J. Ekchian, Kathryn Paisner, and Nathan L. Vanderford

PDF

Downregulation of SREBP Inhibits Tumor Growth and Initiation by Altering Cellular Metabolism in Colon Cancer, Yang-An Wen, Xiaopeng Xiong, Yekaterina Y. Zaytseva, Dana L. Napier, Emma Vallee, Austin T. Li, Chi Wang, Heidi L. Weiss, B. Mark Evers, and Tianyan Gao

PDF

Collagen Prolyl 4-Hydroxylase 1 is Essential for HIF-1α Stabilization and TNBC Chemoresistance, Gaofeng Xiong, Rachel L. Stewart, Jie Chen, Tianyan Gao, Timothy L. Scott, Luis M. Samayoa, Kathleen L. O'Connor, Andrew N. Lane, and Ren Xu

PDF

Extracellular Vesicles Released by Cardiomyocytes in a Doxorubicin-Induced Cardiac Injury Mouse Model Contain Protein Biomarkers of Early Cardiac Injury, Chontida Yarana, Dustin W. Carroll, Jing Chen, Luksana Chaiswing, Yanming Zhao, Teresa Noel, Michael Alstott, Younsoo Bae, Emily V. Dressler, Jeffrey A. Moscow, D. Allan Butterfield, Haining Zhu, and Daret K. St. Clair

PDF

Preclinical Evaluation of Novel Fatty Acid Synthase Inhibitors in Primary Colorectal Cancer Cells and a Patient-Derived Xenograft Model of Colorectal Cancer, Yekaterina Y. Zaytseva, Piotr G. Rychahou, Anh-Thu Le, Timothy L. Scott, Robert M. Flight, Ji Tae Kim, Jennifer Harris, Jinpeng Liu, Chi Wang, Andrew J. Morris, Theru A. Sivakumaran, Teresa Fan, Hunter Moseley, Tianyan Gao, Eun Young Lee, Heidi L. Weiss, Timothy S. Heuer, George Kemble, and B. Mark Evers

Submissions from 2017

PDF

Exploring Cancer Metabolism Using Stable Isotope-Resolved Metabolomics (SIRM), Ronald C. Bruntz, Andrew N. Lane, Richard M. Higashi, and Teresa W. -M. Fan

PDF

Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis, Ravshan Burikhanov, Nikhil Hebbar, Sunil K. Noothi, Nidhi Shukla, James Sledziona, Nathália Araujo, Meghana Kudrimoti, Qing Jun Wang, David S. Watt, Danny R. Welch, Jodi Maranchie, Akihiro Harada, and Vivek M. Rangnekar

PDF

Reversion of Epithelial-Mesenchymal Transition by a Novel Agent DZ-50 via IGF Binding Protein-3 in Prostate Cancer Cells, Zheng Cao, Shahriar Koochekpour, Stephen E. Strup, and Natasha Kyprianou

PDF

M2 Polarization of Macrophages Facilitates Arsenic-Induced Cell Transformation of Lung Epithelial Cells, Jiajun Cui, Wenhua Xu, Jian Chen, Hui Li, Lu Dai, Jacqueline A. Frank, Shaojun Peng, Siying Wang, and Gang Chen

PDF

Loss of Fructose-1,6-Bisphosphatase Induces Glycolysis and Promotes Apoptosis Resistance of Cancer Stem-Like Cells: An Important Role in Hexavalent Chromium-Induced Carcinogenesis, Jin Dai, Yanli Ji, Wei Wang, Donghern Kim, Leonard Yenwong Fai, Lei Wang, Jia Luo, and Zhuo Zhang

PDF

Effect of Cigarette Smoke Exposure and Mutant Kras Overexpression on Pancreatic Cell Proliferation, Howard P. Glauert, R. Scott Elliott, Sung Gu Han, Mark Athey, Eun Young Lee, and C. Gary Gairola

PDF

Size, Shape, and Sequence-Dependent Immunogenicity of RNA Nanoparticles, Sijin Guo, Hui Li, Mengshi Ma, Jian Fu, Yizhou Dong, and Peixuan Guo