This collection was named as Graduate Center for Toxicology Faculty Publications before Jan. 1, 2015.

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Submissions from 2022

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Upregulation of CD36, a Fatty Acid Translocase, Promotes Colorectal Cancer Metastasis by Increasing MMP28 and Decreasing E-Cadherin Expression, James Drury, Piotr G. Rychahou, Courtney O. Kelson, Mariah E. Geisen, Yuanyuan Wu, Daheng He, Chi Wang, Eun Y. Lee, B. Mark Evers, and Yekaterina Y. Zaytseva

Submissions from 2021

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Cellular Origins of EGFR-Driven Lung Cancer Cells Determine Sensitivity to Therapy, Fan Chen, Jinpeng Liu, Robert M. Flight, Kassandra J. Naughton, Alexsandr Lukyanchuk, Abigail R Edgin, Xiulong Song, Haikuo Zhang, Kwok-Kin Wong, Hunter N. B. Moseley, Chi Wang, and Christine F. Brainson

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PI3K/mTOR Dual Inhibitor PF-04691502 Is a Schedule-Dependent Radiosensitizer for Gastroenteropancreatic Neuroendocrine Tumors, Zeta Chow, Jeremy Johnson, Aman Chauhan, Tadahide Izumi, Michael Cavnar, Heidi L. Weiss, Courtney M. Townsend Jr., Lowell B. Anthony, Carrigan Wasilchenko, Matthew L. Melton, Jörg Schrader, B. Mark Evers, and Piotr G. Rychahou

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Innate Immune Activation by Checkpoint Inhibition in Human Patient-Derived Lung Cancer Tissues, Teresa W. M. Fan, Richard M. Higashi, Huan Song, Saeed Daneshmandi, Angela L. Mahan, Matthew S. Purdom, Therese J. Bocklage, Thomas A. Pittman, Daheng He, Chi Wang, and Andrew N. Lane

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Through the Lens: Youth Experiences with Cancer in Rural Appalachian Kentucky Using Photovoice, Katie Gaines, Courtney Martin, Chris Prichard, and Nathan L. Vanderford

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The Use of a Book Club to Promote Biomedical Trainee Professional Development, Jenni Ho, Stacy E. Smith, Erin J. Oakley, and Nathan L. Vanderford

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Cancer Curriculum for Appalachian Kentucky Middle and High Schools, Lauren Hudson, Katherine Sharp, Chris Prichard, Melinda J. Ickes, Sahar Alameh, and Nathan L. Vanderford

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Radioresistance in Prostate Cancer: Focus on the Interplay between NF-κB and SOD, Sameera Kumar and Daret St. Clair

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DNA Repair Pathways in Cancer Therapy and Resistance, Lan-ya Li, Yi-di Guan, Xi-sha Chen, Jin-ming Yang, and Yan Cheng

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NMR Methods for Determining Lipid Turnover via Stable Isotope Resolved Metabolomics, Penghui Lin, Li Dai, Daniel R. Crooks, Leonard M. Neckers, Richard M. Higashi, Teresa W.-M. Fan, and Andrew N. Lane

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RORα Suppresses Cancer-Associated Inflammation by Repressing Respiratory Complex I-Dependent ROS Generation, Wei Mao, Gaofeng Xiong, Yuanyuan Wu, Chi Wang, Daret St. Clair, Jai-Da Li, and Ren Xu

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Untargeted Lipidomics of Non-Small Cell Lung Carcinoma Demonstrates Differentially Abundant Lipid Classes in Cancer vs. Non-Cancer Tissue, Joshua M. Mitchell, Robert M. Flight, and Hunter N. B. Moseley

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Apolipoprotein E Genotype-Dependent Nutrigenetic Effects to Prebiotic Inulin for Modulating Systemic Metabolism and Neuroprotection in Mice via Gut-Brain Axis, Lucille M. Yanckello, Jared D. Hoffman, Ya-Hsuan Chang, Penghui Lin, Geetika Nehra, George Chlipala, Scott D. McCulloch, Tyler C. Hammond, Andrew T. Yackzan, Andrew N. Lane, Stefan J. Green, Anika M. S. Hartz, and Ai-Ling Lin

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Lipid Metabolism as a Targetable Metabolic Vulnerability in Colorectal Cancer, Yekaterina Y. Zaytseva

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Co-Targeting Plk1 and DNMT3a in Advanced Prostate Cancer, Zhuangzhuang Zhang, Lijun Cheng, Qiongsi Zhang, Yifan Kong, Daheng He, Kunyu Li, Matthew Rea, Jianlin Wang, Ruixin Wang, Jinghui Liu, Zhiguo Li, Chongli Yuan, Enze Liu, Yvonne N. Fondufe-Mittendorf, Lang Li, Tao Han, Chi Wang, and Xiaoqi Liu

Submissions from 2020

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ITGA2 Promotes Expression of ACLY and CCND1 in Enhancing Breast Cancer Stemness and Metastasis, Valery Adorno-Cruz, Andrew D. Hoffmann, Xia Liu, Nurmaa K. Dashzeveg, Rokana Taftaf, Brian Wray, Ruth A. Keri, and Huiping Liu

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Resolving Metabolic Heterogeneity in Experimental Models of the Tumor Microenvironment from a Stable Isotope Resolved Metabolomics Perspective, Teresa W-M Fan, Richard M. Higashi, Yelena Chernayavskaya, and Andrew N. Lane

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Spermine Synthase and MYC Cooperate to Maintain Colorectal Cancer Cell Survival by Repressing Bim Expression, Yubin Guo, Qing Ye, Pan Deng, Yanan Cao, Daheng He, Zhaohe Zhou, Chi Wang, Yekaterina Y. Zaytseva, Charles E. Schwartz, Eun Young Lee, B. Mark Evers, Andrew J. Morris, Side Liu, and Qing-Bai She

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A Brief Educational Intervention Enhances Basic Cancer Literacy among Kentucky Middle and High School Students, Lauren Hudson, Kerrigan M. Samons, Haley E. Dicken, Chris Prichard, L. Todd Weiss, Jean Edward, Robin C. Vanderpool, and Nathan L. Vanderford

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Rho GTPases: Big Players in Breast Cancer Initiation, Metastasis and Therapeutic Responses, Brock Humphries, Zhishan Wang, and Chengfeng Yang

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Communication of Professional Readiness in Dietetics and Human Nutrition Undergraduates: A Pilot Study, Heather Norman-Burgdolf, Emily M. DeWitt, Nathan L. Vanderford, and Julie Plasencia

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SOD2 Deficiency in Cardiomyocytes Defines Defective Mitochondrial Bioenergetics as a Cause of Lethal Dilated Cardiomyopathy, Sudha Sharma, Susmita Bhattarai, Hosne Ara, Grace Sun, Daret K. St. Clair, Md Shenuarin Bhuiyan, Christopher Kevil, Megan N. Watts, Paari Dominic, Takahiko Shimizu, Kevin J. McCarthy, Hong Sun, Manikandan Panchatcharam, and Sumitra Miriyala

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IGF-1R Inhibition Induces MEK Phosphorylation to Promote Survival in Colon Carcinomas, Qing Wang, Yan Zhang, Jiang Zhu, Honggang Zheng, Shuntai Chen, Li Chen, and Hsin-Sheng Yang

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Epigenetic Regulation of Prostate Cancer, Ruixin Wang and Xiaoqi Liu

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Develop a High-Throughput Screening Method to Identify C-P4H1 (Collagen Prolyl 4-Hydroxylase 1) Inhibitors from FDA-Approved Chemicals, Shike Wang, Kuo-Hao Lee, Nathália Victoria Araujo, Chang-Guo Zhan, Vivek M. Rangnekar, and Ren Xu