US Patent Number
Nicotine analogs that have nicotinic receptor antagonist properties. These compounds have been shown to competitively inhibit dopamine release induced by nicotine. The nicotine analog compounds are useful in the treatment of nicotine abuse, smoking cessation therapy, as an antidote for nicotine intoxication, treatment of cognitive disorders such as Alzheimer's disease and for the treatment of Parkinson's disease.
University of Kentucky Research Foundation, Lexington, Ky.
Crooks, Peter A.; Dwoskin, Linda P.; and Ravard, Alain, "Nicotinic Receptor Antagonists in the Treatment of Neuropharmacological Disorders" (1997). Pharmaceutical Sciences Faculty Patents. 96.