US Patent Number
A method is provided for producing modified mutant yeast and the resulting yeast that can be used as a platform for terpene production. The method includes chemical mutagenesis to effect ergosterol dependent growth in yeast. Subsequently, these yeast are subjected to an erg9 knockout mutation to thereby produce ergosterol dependent growth/ erg9 knockout mutation yeast cell lines. The resulting yeast are well suited for use in the production of terpenes.
University of Kentucky Research Foundation, Lexington, KY (US)
Chappell, Joseph; Zhuang, Xun; and Wu, Shuiqin, "Method and System for Terpene Production Platforms in Yeast" (2020). Pharmaceutical Sciences Faculty Patents. 193.