US Patent Number
The presently-disclosed subject matter includes compounds including a cyclooxygenase enzyme inhibitor moiety and a moiety derived from a drug of interest. In some embodiments, the drug of interest is an opioid. In some embodiments, the compound includes a diclofenac moiety and a naltrexone or naltrexol moiety. The compounds allow for enhanced delivery rates across skin.
University of Kentucky Research Foundation, Lexington, KY (US)
Stinchcomb, Audra; Kim, Kyung Bo; Pinninti, Ragotham Reddy; Ghosh, Priyanka; and Paudel, Kalpana S., "Compounds Including Cox Inhibitor Moiety and Enhanced Delivery of Active Drugs Using Same" (2017). Pharmaceutical Sciences Faculty Patents. 168.