Semi-Synthetic Mithramycin Derivatives with Anti-Cancer Activity

Authors

Jürgen Rohr, University of KentuckyFollow
Daniel Scott, University of Kentucky
Markos Leggas, University of KentuckyFollow
Jhong-Min Chen, University of KentuckyFollow
Oleg V. Tsodikov, University of KentuckyFollow

US Patent Number

9447135

Publication Date

9-20-2016

Abstract

Mithramycin derivatives and their pharmaceutically acceptable salts are disclosed. The mithramycin derivatives can be used in the treatment of Ewing sarcoma or other cancer or neuro-disease associated with an aberrant erythroblast transformation- specific transcription factor.

Assignees

University of Kentucky Research Foundation, Lexington, KY (US)

Application Number

14/717,542

Filing Date

05/20/2015

Recommended Citation

Rohr, Jürgen; Scott, Daniel; Leggas, Markos; Chen, Jhong-Min; and Tsodikov, Oleg V., "Semi-Synthetic Mithramycin Derivatives with Anti-Cancer Activity" (2016). Pharmaceutical Sciences Faculty Patents. 160.
https://uknowledge.uky.edu/ps_patents/160