US Patent Number
6074674
Publication Date
6-13-2000
Abstract
The present invention provides, inter alia, formulations useful to ameliorate symptoms associated with mucosal abrasions, specifically those due to dental orthodontic brackets; oral surgery; periodontal surgery or other procedures. For instance, there is a formulation comprising: 65 to 75% microcrystalline wax; 5 to 15% non-ionic polymer; 15 to 25% topical anesthetic; and 1 to 5% surfactant, wherein the ratio of non-ionic polymer to microcrystalline wax is no greater than 0.2. Preferably, for solid topical anesthetics, the particle size is less than the apertures of a 100-mesh screen. However, the topical anesthetic may also be a liquid. Formulations wherein the mixture is a homogeneous matrix is preferred.
Assignees
University of Kentucky Research Foundation, Lexington, Ky.
Application Number
09/119,099
Filing Date
07/20/1998
Recommended Citation
Jay, Michael Joseph; Kluemper, G. Thomas; and Kim, Sang Hun, "Formulations for Sustained-Release of Topical Anesthetics and Methods of Making and Using Same" (2000). Pharmaceutical Sciences Faculty Patents. 108.
https://uknowledge.uky.edu/ps_patents/108
