US Patent Number
9,642,845
Publication Date
5-9-2017
Abstract
The invention relates to the use of nicotinic acid alkyl esters, especially myristyl nicotinate, to inhibit side effects associated with retinoic acid therapy. Also a part of the invention is a method for improving skin cell differentiation by administering the nicotinic acid alkyl ester in an amount sufficient to increase expression of caspase 14 and filaggrin. Deficiencies in expression of these molecules can be treated in this way as well.
Assignees
University of Kentucky Research Foundation, Lexington, KY (US)
Application Number
12/449,793
Filing Date
2-27-2008
Recommended Citation
Jacobson, Elaine L.; Jacobson, Myron K.; Coyle, Russell; Kim, Hyuntae; and Coyle, Donna L., "Method for Alleviating Side Effects of Retinoic Acid Therapy and/or Improving Efficacy without Interfering with Efficacy" (2017). Pharmacology and Nutritional Sciences Faculty Patents. 51.
https://uknowledge.uky.edu/pharmacol_patents/51
