US Patent Number

5602309

Publication Date

2-11-1997

Abstract

Transgenic mice that express increased levels of nerve growth factor (NGF) in the epidermis and other stratified, keratinized epithelium. The nerve growth factor expressing transgenic mice are useful in the study of neurodegenerative disorders of the brain such as Parkinson's syndrome and Alzheimer's disease and for testing for drug candidates for the treatment of these diseases.

Assignees

University of Kentucky Research Foundation, Lexington, KY.

Application Number

438,122

Filing Date

05/08/1995

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