US Patent Number
The present invention provides a monoclonal anti-idiotype antibody 3H1 that escapes immune tolerance and elicits a specific immune response to CEA in mice, rabbits, monkeys, and patients with advanced CEA-associated disease. This invention also provides compositions which can be used in the detection or treatment of CEA-associated tumors mimics a specific epitope on carcinoembryonic antigen and a hybridoma that produces 3H1.
The Board of Trustees of the University of Kentucky, Lexington, Ky.
Chatterjee, Malaya; Köhler, Heinz; Chatterjee, Sunil K.; and Foon, Kenneth A., "Murine Anti-Idiotype Antibody 3H1" (1999). Microbiology, Immunology and Molecular Genetics Faculty Patents. 5.